OBJECTIVES To investigate the impact of respiratory motion on localization, and quantification of lung lesions for the Gross Tumor Volume utilizing a fully automated Auto3Dreg program and dynamic NURBS-based cardiac-torso digitized phantom (NCAT). METHODS Respiratory motion may result in more than 30% underestimation of the SUV values of lung, liver and kidney tumor lesions. The motion correc...

Currently in our clinic, a mega-voltage cone beam computed tomography (MVCBCT) scan is performed before each treatment for patient localization. For nonsmall cell lung cancer (NSCLC) patients, a strain gauge is used as an external surrogate to indicate tumor motion in both the planning stage and the treatment stage. However, it is likely that the amplitude of tumor motion varies between treatme...

F. Lohberger, M. Amann, L. R. Schad Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany Introduction Magnetic resonance imaging of the lung is very challenging because of low proton density, cardiac and respiratory motion and susceptibility effects at large number of air/tissue interfaces on small scales. Thereby, the effective transverse relaxation time T2 of lung ...

conclusions this report presents a new method for lung isolation in specific cases and in the absence of certain equipment. case presentation a 41-year-old woman with a history of pharyngo-laryngo-oesophagectomy (plo) and tracheostomy was a candidate for thoracic duct ligation because of chylothorax. since the patient had tracheostmy stomal stenosis, two cuffed tracheal tubes (internal diameter...

In gated radiation therapy procedures, the lung tumor position is used directly (by implanted radiopaque markers) or indirectly (by external surrogate methods) to decrease the volume of irradiated healthy tissue. Due to a risk of pneumothorax, many clinics do not implant fiducials, and the gated treatment is primarily based on a respiratory induced external signal. The external surrogate method...

More than half of all solid tumors receive external beam ionizing radiation as part of multimodality treatment. The goal of radiation treatment is to treat disease while avoiding normal tissue toxicity. In many sites, dose escalation has been shown to offer local tumor control benefits. This has often been reported in the literature addressing irradiation of lung tumors. Lung cancer is the seco...

PURPOSE To develop a novel four-dimensional (4D) intensity modulated radiation therapy (IMRT) treatment planning methodology based on dynamic virtual patient models. METHODS The 4D model-based planning (4DMP) is a predictive tracking method which consists of two main steps: (1) predicting the 3D deformable motion of the target and critical structures as a function of time during treatment del...