Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of the genus Leishmania. It major health problem in many tropical and subtropical regions world can produce three different clinical manifestations, among which cutaneous leishmaniasis has higher incidence than other forms. There are no recognized reliable means chemoprophylaxis or vaccination against infections with f...

Leishmaniasis transmitted by sandflies is an important vector-borne disease. In Chad, information on outdated, and so this study was designed to update the sandfly fauna. Sandflies were collected in five health districts representing two geoclimatic zones using sticky traps pyrethrum sprays indoor peridomestic habitats between September 2019 December 2020. All specimens identified based species...

Leishmaniasis is a zoonotic parasitic disease that affects both humans and animals. Canines are considered the main reservoirs of disease, while cats can present as secondary reservoirs, altering epidemiological cycle disease. The work describes first case feline foot hyperkeratosis in Asunción-Paraguay associated with leishmaniasis, determined by cytological diagnosis, favorable response to tr...

Leishmaniasis is a wide-spectrum disease caused by parasites from Leishmania genus. A well-modulated immune response that established after the long-lasting clinical cure of leishmaniasis can represent standard requirement for vaccine. Previous studies demonstrated (Viannia) naiffi causes benign and its antigens induce responses in vitro. In this work we aimed to identify immunodominant protein...

Diffuse cutaneous leishmaniasis is a rare form of characterized by an inadequate immune response the host cells to parasitic invasion (weak T-helper (Th)1 or Th2 with production interleukin (IL)-4 and IL-10). The characteristic features disease include diffuse nodular eruption, masquerading as leprosy frequent association immunosuppression (HIV co-infection, for example). Russian Federation non...

Whither smooth muscle antibodies in the third millennium? Lupoid hepatitis (now known as autoimmune hepatitis type I) was defined as an autoimmune disease by Mackay and colleagues in 1965. 1 An immunological marker of the disease was identified by Johnson et al in 1965 in the form of an " antismooth muscle antibody ". 2 3 Over the following 30 years, smooth muscle antibody (SMA) has been used i...