OF THE THESIS ....................................................................................... ii ACKNOWLEGEMENT.................................................................................................. iv TABLE OF CONTENTS ................................................................................................. v LIST OF TABLES ..............................................

Since 1938 when Goetsch studied injected surgical specimens, the growth of cystic hygromas has always been considered as a continuous budding from the walls of the tumour cavity. This phenomenon was compared to the foetal centrifugal development of peripheral lymphatics from the walls of the primary lymphatic sacs, in keeping with Florence Sabin's theory of lymphatic embryology (1912). Although...

WoundCareAdvisor.com 25 Imagine you have a health condition that affects your life every day. Then imagine being told nothing can be done about it; you’ll just have to live with it. Or worse yet, your physician tells you the problem is “you’re just fat.” Many people with lymphedema or lipedema have no idea their condition has a name or that many other people suffer from the same thing. Although...

However, in many infections the effect on the lymphatics may be both consistent and clinically marked. The lymphadenopathy may be local or generalized and lymphadenopathy is or can be a significant feature of acute HIV infection, primary Herpes simplex, some rickettsial infections, tularaemia, plague, cat-scratch fever due to Bartonella henselae, primary syphilis, lymphogranuloma venereum, chan...

The lymphatic system consists of a fluid, lymph, a network of lymphatic vessels, specialized cells called lymphocytes, and an array of lymphoid tissues and lymphoid organs scattered throughout the body. This system has three major functions: (1) to protect the body through the immune response; (2) to transport fluid from the interstitial fluid to the bloodstream; and (3) to help distribute horm...

The lymphatic vascular system plays an important role in the maintenance of fluid homeostasis, in the afferent immune response, in the intestinal lipid uptake and in the metastatic spread of malignant cells. The recent discovery of specific markers and growth factors for lymphatic endothelium and the establishment of genetic mouse models with impairment of lymphatic function have provided novel...

Much effort has been made to achieve lymphatic targeting of drugs using colloidal carriers. This paper reviews the recent progress in the development of biodegradable nanoparticulate systems, including nanospheres, emulsions, and liposomes. The major purpose of lymphatic targeting is to provide an effective anticancer chemotherapy to prevent the metastasis of tumor cells by accumulating the dru...

The lymphatic system, also named the second vascular system, plays a critical role in tissue homeostasis and immunosurveillance. The past two decades of intensive research have led to the identification and detailed understanding of many molecular players and mechanisms regulating the formation of the lymphatic vasculature during embryonic development. Furthermore, clinical and experimental dat...

The lymphatic system is a vital part of the circulatory and immune systems, and plays an important role in homeostasis by controlling extracellular fluid volume and in combating infection. Nevertheless, there is a notable disparity in terms of research effort expended in relation to the treatment of lymphatic diseases in contrast to the cardiovascular system. While similarities to the cardiovas...

lop? This question is as simple as it is fundamental to the understanding of the lymphatic system (LS) under physiological and pathological conditions. Moreover, it is also critical for the development of therapeutic interventions. In 1902, the anatomist Florence Sabin published her studies on the development of the earliest lymphatic vessels in pigs [1 ] and thereby laid the foundation for a c...