The allospecifc T cell population responding to a transplanted organ consists of both naive and memory lymphocytes. Although it is established that naive T cells are activated by antigen within the organized structures of secondary lymphoid organs (the spleen, lymph nodes, and mucosal lymphoid tissues), it is not clear whether memory T cell activation and propagation depend on homing to these o...

Dendritic cells are present in both lymphoid and non-lymphoid organs, which heterogenous group of nonphagocytic nonlymphoid immune accessory cells. Plasmacytoid dendritic cell (which has an eccentric nuclei) subset aid secreting high levels type 1 interferons by activation gaining like morphology, play important role antiviral immunity involved initiation development stages inflammatory respons...

Before embarking on a study of the lymphoid system of an amphibian larva, it is necessary to realize that lymphoid tissue may occur in many organs of the body and that in all immature vertebrates and in adult poikilotherms separation of lymphoid tissue from myeloid tissue is incomplete (Yoffey, 1960). Jordan (1938) reviewed the early work on the haemopoietic tissues of Amphibia. Cooper (1967tf,...

The recent discovery of a receptor needed for lymphocyte migration into lymphoid follicles indicates that multiple chemoattractive gradients allow lymphocytes to navigate to specialized niches in lymphoid organs.

Lymphoid neogenesis is traditionally viewed as a pre-programmed process that promotes the formation of lymphoid organs during development. Here, the spatial organization of T and B cells in lymph nodes and spleen into discrete structures regulates antigen-specific responses and adaptive immunity following immune challenge. However, lymphoid neogenesis is also triggered by chronic or persistent ...

A population of lymphoid cells from several animal species, including man, was identified through a membrane receptor which binds sheep red blood cells treated with antibody and complement. When cells from different lymphoid organs were incubated with EAC at 37 degrees C, only part of the lymphocytes (named CRL) bound EAC and formed rosettes, and this interaction was shown to be C3-dependent. M...

Investigations during the past ten years have formed the basis for the working hypothesis that pituitary-adrenal cortical secretion exerts an influence on the structure and function of lymphoid tissue. The administration to rats of adrenal cortical extract, or of adrenal cortical steroids oxygenated in position 11 of the steroid nucleus, produced marked thymic atrophy.''" ' 2 40 448 Experiments...

Visna/Maedi virus (VMV), a small ruminant lentivirus responsible for lymphoproliferative pneumonia, encephalitis, arthritis and/or mastitis in sheep, has been detected in different non-lymphoid organs. However, only a few investigations have been carried out in lymphoid tissues. In this study, some lymphoid tissues and lymph node draining or non-draining VMV target organs from five sheep infect...