BACKGROUND Russia and Eastern Europe have one of the fastest growing HIV epidemics in the world. While countries in this region have implemented HIV testing within addiction treatment systems, linkage to HIV care from these settings is not yet standard practice. The Linking Infectious and Narcology Care (LINC) intervention utilized peer-led strengths-based case management to motivate HIV-infect...

The genetic information of eukaryotic cells is enclosed within a double-layered nuclear envelope, which comprises an inner and outer nuclear membrane. Several transmembrane proteins locate to the nuclear envelope; however, only two integral protein complexes span the nuclear envelope and connect the inside of the nucleus to the cytoplasm. The nuclear pore complex (NPC) acts as a gateway for mol...

Background:Pigmented lesions with clinical features suspicious for melanoma are not uncommon in pediatric patients. Evaluation of these is complicated by the low prevalence and challenges associated performing biopsies children. The DermTech Melanoma Test (‘the test’) a non-invasive genomic test designed to rule out melanoma. It consists Pigmented Lesion Assay (PLA), which detects RNA gene expr...

Wireless broadband digital communication systems are facing more and more critical power efficiency problems. Crest Factor (PAPR) is reported to be in 10-12dB range for WiMAX 802.16e systems implementing OFDM IFFT-1024 and 64-QAM modulation. In this work, outphasing (LINC) and Polar transmitter architectures are investigated and compared with Direct Conversion architecture. Complete system solu...

objective(s): similar characteristics of molecular pathways between cellular reprogramming events and tumorigenesis have been accentuated in recent years. reprogramming-related transcription factors, also known as yamanaka factors (oct4, sox2, klf4, and c-myc), are also well-known oncogenes promoting cancer initiation, progression, and cellular transformation into cancer stem cells. long non-co...

Emerging evidence indicates that the dysregulation of long non-coding RNAs (lncRNAs) contributes to the development and progression of lung adenocarcinoma (LAD), however the underlying mechanism of action of lncRNAs remains unclear. It is well known that the effective treatment of cancers has been hindered by drug resistance in the clinical setting. Epithelial-mesenchymal transition (EMT) has b...