Magnetic nanoparticles can bind to different drug delivery systems and can be used for drug targeting to a specific organ by using an external magnetic field as well as used in hyperthermia by heating in alternating magnetic fields. The characteristics of iron oxide nanoparticles are significantly affected by particle size, shape and zeta potential, among which the particle size plays the most ...

Novel multifunctional magnetic-mesoporous Janus particles with controlled aspect ratio were developed by a simple one-step synthesis approach. Due to their superior magnetic properties and well-defined pore structures, these particles will be important in drug delivery, molecule targeting, cellular imaging, and as building blocks for the assembly of complex nanostructures.

A combination of magnetic hyperthermia and magnetothermally-facilitated drug release system was developed as a promising strategy for liver cancer therapy. The thermosensitive copolymer, 6sPCL-b-P(MEO2MA-co-OEGMA) shows a good temperature-controlled drug release response. Mn-Zn ferrite magnetic nanoparticles (MZF-MNPs) exhibit a strong magnetic thermal effect with an alternating magnetic field ...

Arrays of permanent magnet elements have been utilized as light-weight, inexpensive sources for applying external magnetic fields in magnetic drug targeting applications, but they are extremely limited in the range of depths over which they can apply useful magnetic forces. In this paper, designs for optimized magnet arrays are presented, which were generated using an optimization routine to ma...

The use of stents for vascular disease has resulted in a paradigm shift with significant improvement in therapeutic outcomes. Polymer-coated drug-eluting stents (DES) have also significantly reduced the incidence of reobstruction post stenting, a disorder termed in-stent restenosis. However, the current DESs lack the capacity for adjustment of the drug dose and release kinetics to the disease s...

The technique of magnetic drug targeting consists of binding genetic material or drugs to superparamagnetic nanoparticles and accumulating them via an external magnetic field in a target region. However, it is still a challenge for this approach to succeed in areas with high flow rates, like the aorta or the heart ventricle. The magnetic field sources have to be accurately optimized and adapted...

BACKGROUND Nanomaterials are at the leading edge of the rapidly developing field of nanotechnology. Magnetic nanoparticles for cancer therapy and diagnosis have been developed on the basis of their unique physico-chemical properties not present in other materials. Their versatility is widely exploited in such diverse techniques as cell and macromolecule separation and purification, immunoassays...

We have designed a new magnetic targeting drug carrier Fe3O4-PVA with core of triiron tetroxide (Fe3O4) and shell made polyvinyl alcohol (PVA) to improve the hydrophilicity Fe3O4. With adriamycin hydrochloride as model drug, this study goes on measure performance Fe3O4-PVA. In addition, thermal stability enthalpy decomposition were measured using differential scanning calorimeter non-isothermal...