The male factor is considered a major contributory factor to infertility. Apart from the conventional causes for male infertility such as varicocoele, cryptorchidism, infections, obstructive lesions, cystic fibrosis, trauma, and tumours, a new and important cause has been identified: oxidative stress. Oxidative stress is a result of the imbalance between reactive oxygen species (ROS) and antiox...

Male are the sole cause of infertility in approximately 20% of infertile couples and are an important contributing factor in another 20-40% of couples with reproductive failure. Male infertility can result from a variety of causes. Some, like ductal obstruction and hypogonadotropic hypogonadism, can be accurately defined and effectively treated. Genetic abnormalities can cause infertility by in...

the number of couples seeking consultation for infertility problems has steadily increased over the past decade, affecting 10%-15% of the sexually active population. abnormal semen production, a male factor infertility (mfi), is thought to be the cause of up to 50% of all infertilities in developed countries. there are potentially many different causes of male infertility, including hormonal, a...

being either underweight or overweight can affect a woman's fertility. irregular menstrual cycles, reduced spontaneous and assisted fertility and an increased risk of miscarriage are risks associated with obesity that are often overlooked. excessive weight and central distribution of body fat are both related to an increased risk of normogonadotrophic anovulation. weight loss can re-establish o...

background: microdeletions of the azoospermia factor locus of the long arm of y chromosome are an etiological factor of severe oligozoospermia or azoospermia. objective: the aim of this study was to investigate the prevalence of y-chromosome microdeletions in azf region and their role in infertility in pakistani population. materials and methods: the type of deletions in azf locus were detected...

Human Andrology 2011, 1:2–16 Objective To highlight the concept of unexplained male infertility and discuss the potential causes and its proper management. Design Review of literature. Results Male infertility of unknown origin is a condition in which fertility impairment occurs spontaneously or due to an obscure or unknown cause. It includes two categories, unexplained male infertility and idi...

Approximately 15% of human couples are affected by infertility, and about half of these cases of infertility can be attributed to men, through low sperm motility (asthenozoospermia) or/and numbers (oligospermia). Because mitochondrial genome (mtDNA) mutations are identified in patients with fertility problems, there is a possibility that mitochondrial respiration defects contribute to male infe...

Microsurgical training is imperative for urologists and clinical andrologists specializing in male infertility. Success in male infertility microsurgery is heavily dependent on the surgeon's microsurgical skills. Laboratory-based practice to enhance microsurgical skills improves the surgeon's confidence, and reduces stress and operating time, benefiting both the patient and the surgeon. This re...