maryam mousavinezhad-moghaddam department of physiology, biology division, faculty of sciences, ferdowsi university of mashhad, mashhad, iran abbas ali amin department of immunology, faculty of medicine, kurdistan university of medical sciences, sanandaj, iran houshang rafatpanah immunology research centre, bu-ali research institute, mashhad university of medical sciences, mashhad, iran seyed abdol rahim rezaee inflammation and inflammatory diseases research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran