نتایج جستجو برای: mcs

تعداد نتایج: 5328  

2016
Yuko Muroyama Atsushi Baba Motoo Kitagawa Tetsuichiro Saito

Mitral cells (MCs) of the mammalian olfactory bulb have a single primary dendrite extending into a single glomerulus, where they receive odor information from olfactory sensory neurons (OSNs). Molecular mechanisms for controlling dendritic arbors of MCs, which dynamically change during development, are largely unknown. Here we found that MCs displayed more complex dendritic morphologies in mous...

Journal: :Blood 2003
Shigeru Okumura Jun-ichi Kashiwakura Hisashi Tomita Kenji Matsumoto Toshiharu Nakajima Hirohisa Saito Yoshimichi Okayama

Rodent mast cells (MCs) are reported to play a pivotal role in both innate and adaptive immunity. However, there is so far no evidence that human MCs are involved in innate immunity. We found that a functional Toll-like receptor 4 (TLR4) was expressed on human MCs when it was up-regulated by interferon gamma (IFN-gamma). To systematically explore how human MCs modulate the immune system followi...

2017
You-Chao Tang Ying-Jie Shi Shi-Guang Huang

This study was undertaken to investigate the distribution of mast cells (MCs) and the expression of transforming growth factor-β (TGF-β) on tryptase positive MCs in different types of human periapical diseases. Periapical tissues of 78 participates were used in this study, including healthy control (n=28), periapical cyst (n=25), and periapical granuloma (n=25). The tissue samples were fixed in...

Journal: :Advanced pharmaceutical bulletin 2015
Maryam Kouhsoltani Monir Moradzadeh Khiavi Golshan Jamali Samira Farnia

PURPOSE The aim of this study was to verify the density of mast cells (MCs) and microvessels in odontogenic cysts. Furthermore, the correlation between MCs and microvessels was evaluated to assess the contribution of MCs to angiogenesis and growth of odontogenic cysts. This approach may be a basis for the development of future pharmaceuticals addressed to MCs performance to manage odontogenic c...

2015
Wenhua Song Xiangde Li Jun Qian Guoyu Lv Yonggang Yan Jiacan Su Jie Wei

Mesoporous calcium-silicon xerogels with a pore size of 15 nm (MCS-15) and pore volume of 1.43 cm(3)/g were synthesized by using 1,3,5-mesitylene (TMB) as the pore-expanding agent. The MCS-15 exhibited good degradability with the weight loss of 50 wt% after soaking in Tris-HCl solution for 56 days, which was higher than the 30 wt% loss shown by mesoporous calcium-silicon xerogels with a pore si...

Journal: :Colloids and surfaces. B, Biointerfaces 2015
Zhanfeng Li Fengzhi Xu Quanshun Li Songfeng Liu Hongyan Wang Helmuth Möhwald Xuejun Cui

Multifunctional folic acid conjugated BSA@Fe3O4 microcapsules (FA-BSA@Fe3O4 MCs) have been prepared successfully based on the sonochemical method. The as-synthesized FA-BSA@Fe3O4 MCs have a suitable size range for biomedical applications, and a high loading capacity for water-insoluble drugs. Furthermore, FA-BSA@Fe3O4 MCs show excellent magnetic properties. Cytotoxicity tests indicate that FA-B...

Journal: :Environmental Health Perspectives 2002

2009
Martin L. Pall

Cases of multiple chemical sensitivity (MCS) are reported to be initiated by seven classes of chemicals. Each of the seven acts along a specific pathway, indirectly producing increases in NMDA activity in the mammalian body. Members of each of these seven classes have their toxicant responses lowered by NMDA antagonists, showing that the NMDA response is important for the toxic actions of these...

2017
Thomas M Dantoft Sine Skovbjerg Linus Andersson Anna-Sara Claeson Kaare Engkilde Nina Lind Steven Nordin Lars I Hellgren

OBJECTIVES To investigate the pathophysiological pathways leading to symptoms elicitation in multiple chemical sensitivity (MCS) by comparing gene expression in MCS participants and healthy controls before and after a chemical exposure optimised to cause symptoms among MCS participants.The first hypothesis was that unexposed and symptom-free MCS participants have similar gene expression pattern...

2015
Theoharis C. Theoharides Julia M. Stewart

Mast cells (MCs) are ubiquitous in the body, but they have historically been associated with allergies, and most recently with regulation of immunity and inflammation. However, it remains a puzzle why so many MCs are located in the diencephalon, which regulates emotions and in the genitourinary tract, including the bladder, prostate, penis, vagina and uterus that hardly ever get allergic reacti...

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