Introduction Cleft lip and palate (CLP) is one of the most common types of congenital malformation. Cleft lip is caused by failure of fusion of the median and lateral nasal processes while cleft palate (CP) is caused by failure of fusion of the palatal shelves of the maxillary process. The mean incidence of orofacial clefts locally over the past 10 years is 0.2%. The aetiology of CLP is multifa...

Although it is a rare developmental malformation, van der Woude syndrome is the most common form of syndromic orofacial clefting, accounting for approximately 2% of all cleft cases. The lower lip pits with or without a cleft lip or palate is characteristic of the syndrome. Findings, such as hypodontia, limb deformities, popliteal webs, ankylogossia, ankyloblepheron, and genitourinary and cardio...

OBJECTIVES/HYPOTHESIS To evaluate the prevalence and unmet need for cleft lip-cleft palate reconstructive surgery by using incidence. Our hypotheses were that the age of presentation to screening clinics will decrease between 2006 and 2012, and the geospatial distribution of cases will expand to a more rural catchment area. STUDY DESIGN Longitudinal cross-sectional/geospatial distribution stu...

Besides the geometrical tortousity due to the extrasynaptic structures, macromolecular crowding and geometrical irregularities constituting the cleft composition at central excitatory synapses has a major and direct role in retarding the glutamate diffusion within the cleft space. However, the cleft composition may not only coarsely reduce the overall diffusivity of the glutamate but may also l...

Non-syndromic (NS) cleft lip (CL) and with palate (CLP) are abnormalities in the orofacial area that not accompanied by head neck have normal physical growth cognitive development. Cleft CLP caused two factors, genetic environmental factors which include deficiencies of micronutrients such as folate vitamin B12. This study aimed to determine differences B12 serum levels between mothers whose ch...

NNIN REU Site: Nanotechnology Research Center, Georgia Institute of Technology, Atlanta, GA NNIN REU Principal Investigator: Dr. Ravi V. Bellamkonda, Neurological Biomaterials and Cancer Therapeutics Lab, Department of Biomedical Engineering, Georgia Institute of Technology NNIN REU Mentor: Dr. S.Balakrishna Pai, Neurological Biomaterials and Cancer Therapeutics Lab, Department of Biomedical En...

The  present study aims at exploring the processing difficulty of cleft structures as a type of relative clause for EFL and Persian as  first language learners.The impact of head nouns with various functions as well as that of embedding on the processing of Persian and English cleft structures has been investigated in the present study.The participants  were 68  Iranian male and female students...

HYPOTHESIS Refractory pilonidal disease is due to damage of the epidermis in the deep gluteal cleft by moisture and bacteria, rather than to damage in deep tissues. A new paradigm suggests that a procedure to change the shape of the gluteal cleft will improve results. DESIGN Before-and-after trial. SETTING Community private practice with extensive experience in pilonidal disease, providing ...

OBJECTIVE The purpose of this study was to determine the difference in prevalence of the different categories of facial cleft deformities between the white and black patients in a database of 2806 cleft cases at the University of Pretoria. No variation of clefts between these two groups has ever been compared previously. For this purpose, the clefts were classified according to the system descr...