The paper deals with medicinal plants used in various traditional systems of medicine in Lohit, Dibang Valley and Lower Dibang valley districts of Arunachal Pradesh. The three adjoining districts are located in the extremity of the state bounded by China in the Northeastern part, Changlang district of Arunachal Pradesh in the Southeastern part; state of Assam in the Southwest as well as East Si...

Ethno-medicinal research in district Kathua was conducted during the period 2010 to 2012. The objective of the research was the assessment and preservation of cultural and traditional knowledge of medicinal plants of the area. A checklist of the ethno-medicinal flora has been produced which includes 139 species belonging to 117 genera and 69 families. Information on the medicinal uses gathered ...

Structure Activity Relationship forms the basis of Rational Drug Design in the circles of pharmaceutical and medicinal chemistry. Appropriate knowledge of functional outcomes of structural modifications is crucial in conferring desired pharmacological properties to a chemical compound. Amiodarone is a classical antiarrythmic agent with a long list of adverse effects. This article attempts to re...

The importance of stereochemistry for medicinal chemistry and pharmacology is well recognized and the dissimilar behavior of enantiomers is fully documented. Regarding the environment, the significance is equivalent since enantiomers of chiral organic pollutants can also differ in biodegradation processes and fate, as well as in ecotoxicity. This review comprises designed biodegradation studies...

Mehmet A. OTURAN, Maurice MÉDEBIELLE Université Paris 7 Denis Diderot, Laboratoire d’Electrochimie Moléculaire, UMR CNRS 7591, Case courrier 7107, 2 Place Jussieu, 75251 Paris Cedex 05-FRANCE e-mail: [email protected] Shirish A. PATIL, Robert S. KLEIN Albert Einstein College of Medicine Cancer Centre and Medicinal Chemistry Laboratory, Department of Oncology, Montefiore Medical Centre, Bronx, ...

Recently, heterocyclic compounds analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The small and simple thiadiazole nucleus possesses numerous biological properties like antitumor, antimicrobial, anti-inflammatory, anticonvulsant, and antidiabetic activities. These activities are also possessed by its su...

1 Department of Biological Sciences, Purdue University, West Lafayette, IN, United States, 2 Bindley Bioscience Center, Purdue University, West Lafayette, IN, United States, 3 Purdue Institute for Drug Discovery, Purdue University, West Lafayette, IN, United States, 4 Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States, 5 Purdue Ins...

Traditional medicinal chemistry paradigms, relying initially on ‘wet’ chemistry followed by screening and lead optimizations, are expensive and time consuming. On the other hand, initial in silico screening that guides the synthesis and screening of selected compounds has proven to be a better approach to accelerate drug discovery and reduce the cost of the discovery phase. The Special Focus is...

The “Journées Franco-Belges de Pharmacochimie” is a recognized two-day annual meeting on Medicinal Chemistry that is renowned for the advanced science presented, conviviality, and outstanding opportunities for senior and young scientists to exchange knowledge. Abstracts of plenary lectures, oral communications, and posters presented during the meeting are collected in this report.