A novel proton exchange membrane has been prepared using sulfonated poly(styrene-divinylbenzene) resin(SPSDR)–polyethylene(PE). The membrane is characterized by FT-IR, SEM and TGA/DSC. Water uptake, oxidative resistance, ionic conductivity and methanol permeability are measured to evaluate its performance in a direct methanol fuel cell. The on-set degradation temp...

The studies on the resistance to degradation of capillary polypropylene membranes assembled in a membrane crystallizer were performed. The supersaturation state of salt was achieved by evaporation of water from the NaCl saturated solutions using membrane distillation process. A high feed temperature (363 K) was used in order to enhance the degradation effects and to shorten the test times. Salt...

Membrane proteins make up ∼30% of the proteome. During the early stages of maturation, this class of proteins can experience localized misfolding in distinct cellular compartments, such as the cytoplasm, endoplasmic reticulum (ER) lumen and ER membrane. ER quality control (ERQC) mechanisms monitor folding and determine whether a membrane protein is appropriately folded or is misfolded and warra...

Radical-induced degradation of proton exchange membranes limits the durability proton-exchange membrane fuel cells. Cerium is widely used as a radical scavenger, but migration cerium ions to the...

Cells must regulate the abundance and activity of numerous nutrient transporters in different organelle membranes to achieve nutrient homeostasis. As the recycling center and major storage organelle, lysosomes are essential for maintaining nutrient homeostasis. However, very little is known about mechanisms that govern the regulation of its membrane proteins. In this study, we demonstrated that...

Protective protein/cathepsin A (PPCA) has a serine carboxypeptidase activity of unknown physiological function. We now demonstrate that this protease activity triggers the degradation of the lysosome-associated membrane protein type 2a (lamp2a), a receptor for chaperone-mediated autophagy (CMA). Degradation of lamp2a is important because its level in the lysosomal membrane is a rate-limiting st...

Identical location transmission electron microscopy (IL-TEM) is a powerful technique that has previously been used to study degradation of catalyst materials for proton exchange membrane fuel cells (PEMFCs) in half-cell...

Among the synthetic polymers, polyurethanes are one of the most important polymers applied in Tissue Engineering (TE). Their segmented block structure enables the control of different properties, such as, biocompatibility, blood compatibility, mechanical properties and also biodegradability. In this work, polyurethane membranes were obtained using the electrospinning apparatus. Fibroblasts cell...

Lysosomes are acidic compartments filled with more than 60 different types of hydrolases. They mediate the degradation of extracellular particles from endocytosis and of intracellular components from autophagy. The digested products are transported out of the lysosome via specific catabolite exporters or via vesicular membrane trafficking. Lysosomes also contain more than 50 membrane proteins a...