Meningiomas are the second-most common intracranial tumours in adults. They are derived from the arachnoid cells, and although approximately 90% of meningiomas are benign, more than half of all meningiomas develop peritumoral brain oedema (PTBE), which increases morbidity. The PTBE can be treated with steroid therapy, but this treatment is not specific, is not always effective, and involves lon...

Intraventricular meningiomas are uncommon intracranial tumors and infrequently present with hemorrhage. With only 10 reported cases in the literature, it is exceedingly rare for meningiomas of the ventricular system to present with hemorrhage. To our knowledge, this is the first report of a patient presenting with an acute intraventricular hemorrhage in relation to a ventricular meningioma susp...

Yet meningiomas have characteristic neuroimaging features, some other lesions are still confusing with meningiomas. The aim of this study was trying to find the typical (1)H-MRS metabolic factors of histologic subtyped meningiomas, schwannomas, metastases, and other brain tumors for differential diagnosis among them. (1)H-MRS using STEAM (TE/30 ms, TR/2 sec) and PRESS (TE/288 ms, TR/2 sec) sequ...

PRIMARY intra-orbital meningiomas are rather uncommon, and primary intraorbital meningiomas unattached to the optic nerve sheath are decidedly rare. Scarpa (1816) was quoted by Byers (1901) as being the first to have reported an intraorbital meningioma. Goar (1926) and Mayer (1928) estimated the number of intra-orbital meningiomas in the literature at 40, but there was no clear indication in ma...

PURPOSE To assess MR and pathologic characteristics of childhood intracranial meningiomas, comparing the radiographic findings with those observed in adult intracranial meningiomas. METHODS Clinical records, MR and CT scans, and histology of eight children with intracranial meningiomas presenting for a period of 7.5 years were retrospectively reviewed. RESULTS Boys equaled girls but predomi...

CD44 molecules play an important role in cell adhesion, interaction between cells and extracellular matrix and cellular invasive growth potential. The aim of the study was to evaluate CD44 expression in atypical and benign meningiomas. The tumor specimens were obtained from 61 patients (27 males and 34 females; aged 19 - 78). The analysed material included 10 atypical meningiomas (G2), and foll...

Grossly term meningiomas describe group of tumours arising from meninges. It is a slow growing tumour. It can involve any age group and gender, however it is more common in elderly and in females. It is most common secondary malignancy attributed to radiation exposure. World Health Organization typically classifies it in three different grades. Grade I is benign, grade II atypical and grade III...

OBJECT To determine the indications for surgery in patients harboring asymptomatic meningiomas, the authors retrospectively analyzed the natural course and surgical outcome of asymptomatic meningiomas and then compared these to the natural course and surgical outcome of symptomatic meningiomas. METHODS Between 1989 and 2003, 1434 patients harboring meningiomas, who were treated in Kumamoto Pr...

BACKGROUND Meningiomas are known to recur frequently, and their longterm management remains controversial. Previous studies indicate that progesterone and its receptors can play a role in the recurrence of meningiomas, but the correlation between the presence of these receptors and patients' outcome is unclear. AIM To conduct a retrospective analysis to investigate the prognostic relevance of...

Learning Objectives: After reading this article, the participant should be able to: 1. Identify the surgical anatomy and approaches to the foramen magnum region. 2. Recall the transcondylar approach to foramen magnum meningiomas. 3. Describe the suboccipital approach to foramen magnum meningiomas. 4. Explain the postoperative care and complications related to surgical techniques offoramen magnu...