Psychiatric and neurologic disorders take an enormous toll on society. Alleviating the devastating symptoms and consequences of neuropsychiatric disorders such as addiction, depression, epilepsy, and schizophrenia is a main force driving clinical and basic researchers alike. By elucidating these disease neuromechanisms, researchers hope to better define treatments and preventive therapies. Rese...

This study compared the temporal organization of graphic movements executed either actually or mentally. Six subjects had to perform two tasks, writing a sentence and drawing a cube, either as a real performance or as an imagined one, with either the right or the left hand, and with either a small or a large tracing amplitude. In the same subject, for the same hand, mental and actual movement t...

Unfortunately, many people, including many psychotherapists, mistakenly think that Obsessive-compulsive disorder (OCD) in children and adolescents is rare. Recent research indicates that approximately half of all adults with OCD experience clinical symptoms of the disorder during their childhood. OCD in childhood is a chronic and distressing disorder that can lead to severe impairments in socia...

We provide a model of non-redundant credit default swaps (CDSs), building on the observation that CDSs are more liquid than bonds. CDS introduction involves a trade-o↵: It crowds out demand for the bond, but improves the bond allocation because it allows long-term investors to become levered basis traders. CDS introduction raises bond prices only when there is a significant liquidity di↵erence ...

Complex real-time systems must integrate physical processes with digital control, human operation and organisational structures. New scientific foundations are required for specifying, designing and implementing these systems. One key challenge is to cope with the wide range of time scales and dynamics inherent in such systems. To exploit the unique properties of time, with the aim of producing...