Objectives The aim was to identify theoretically expected as well as actually reported benefits from drug development and the importance of individual patient benefits compared to the collective benefits to society in general. Background Ethical guidelines require that clinical research involving humans offer the potential for benefit. A number of characteristics can be applied to define rese...

Dharmakīrti （c. A.D. 600-660） mentioned two examples of esoteric literature in his Pramāṇavārttikasvavṛtti: the Ḍākinītantra and Bhaginītantra. Karṇakagomin 9-10th century） rephrased Bhaginītantra as Caturbhaginītantra （The Tantra Four Sisters） commentary on Pramāṇavārttikasvavṛtti titled Pramāṇavārttikaṭīkā. An earlier study presumed that Sisters here were four goddesses Jayā, Vijayā, Ajitā/Ja...

Current research refers to videogames as a constant variable. However, games today are designed to be highly interactive and versatile: two players may be using the same videogame, but as a result of different using patterns, the game will not necessarily encompass the same content and gameplay. The current study examined the possible relationship between psychopathology and in-game playing pat...