Abstract Background and Aims Henoch - Schӧnlein purpura (HSP) is an immuno-mediated small-vessel vasculitis that manifests as non—thrombocytopenic purpura, arthritis or arthralgia, abdominal pain and/or kidney involvement. HSP nephritis can presented micro- macroscopic hematuria, proteinuria, nephrotic nephritic syndrome, well acute renal failure. The aim of the study to identify risk factors a...

Despite extensive study of the immunological events in acute serum sickness in rabbits (1-3), the mechanism of glomerular inflammation and injury seen in this model has remained obscure (3). It has generally been thought that the glomerular inflammation, like the vasculitis, results from the activation of humoral mediator systems by deposited immune complexes, but no such mediator system has be...

To demonstrate that Ochratoxin A can cause kidney failure as the kidney is the primary target for OTA cytotoxicity. Ochratoxin A (OTA) is a mycotoxin found in our food. The cytotoxic effect of a low cumulative dose of OTA on the renal corpuscles of the kidney tissue has been investigated in this report. This study was based on two groups in which weaning albino rats were used: (1) control; (2) ...

Background Henoch - Schӧnlein purpura (HSP) is an immuno-mediated small-vessel vasculitis that manifests as non—thrombocytopenic purpura, arthritis or arthralgia, abdominal pain and/or kidney involvement. HSP nephritis can presented micro- macroscopic hematuria, proteinuria, nephrotic nephritic syndrome, well acute renal failure {1,2}. Objectives The aim of the study to identify risk factors as...

The pathologic evaluation of tumor nephrectomy specimens focuses on the diagnosis, grading, and staging of the neoplasm. The presence of coincidental non-neoplastic diseases in these specimens may have significant implications for patient outcomes. The purpose of this study is to determine the spectrum of non-neoplastic disease processes that may be overlooked in tumor nephrectomies, and to asc...

Prof. Emilio Bucciarelli, Istituto di Anatomia e Istologia, Patologica Policlinico Monteluce, PO Box 54, I-06100 Perugia (Italy) Dear Sir, Congenital nephrotic syndrome of the Finnish type (CNS) is a rare recessively inherited disorder with invariably fatal outcome in infancy [1]. CNS was initially observed in Finland, where it remains most common; however, familial and sporadic cases have been...

background: there is evidence that mesangial cell structural changes contribute to the pathogenesis of diabetic nephropathy. to gain better insight into the mechanisms responsible for this issue, present study focused on effect of cord blood mononuclear cells (mncs) derived cd133 positive cells on mesangial cell structure and function. materials and methods: the animals were randomly divided in...

Background: There is evidence that mesangial cell structural changes contribute to the pathogenesis of diabetic nephropathy. To gain better insight into the mechanisms responsible for this issue, present study focused on effect of cord blood mononuclear cells (MNCs) derived CD133 positive cells on mesangial cell structure and function. Materials and Methods: The animals were randomly divided in...