نتایج جستجو برای: mest
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هدف از پژوهش حاضر، بررسی تأثیر سرکوب خاطره منفی بر اختصاصی بودن حافظه سرگذشتی، نشخوار و میزان مزاحمت خاطره منفی، و نیز مقایسه اثربخشی آموزش اختصاصی سازی حافظه سرگذشتی، درمان شناختی-رفتاری و درمان دارویی در بیماران افسرده بود. دو مطالعه این پژوهش، تجربی و طرح آن پیش آزمون –پس آزمون همراه با گروه کنترل بود. به منظور بررسی اثر سرکوب، 30 بیمار افسرده سرپایی که در سال 1390به مراکز مشاوره ومطب روانپز...
Mixed epithelial and stromal tumor (MEST) of the kidney belongs to broad spectrum renal neoplasms, distinguished by their varying composition components. The histopathological display biphasic growth pattern mesenchymal elements, often with estrogen progesterone receptor positivity, clinches diagnosis. It is typically benign, low recurrence rates excellent prognosis after surgical resection. ME...
This paper is concerned with the multivariate extended skew-normal [MESN] and skew-Student [MEST] distributions, that is, distributions in which location parameters of underlying truncated are not zero. The extra parameter leads to greater variability moments critical values, thus providing flexibility for empirical work. It reported this various theoretical properties notably limiting forms as...
Background. IgA nephropathy is the most common cause of primary glomerulonephritis in China, and Traditional Chinese Medicine (TCM) is a vital treatment strategy. However, not all doctors prescribing TCM medicine have adequate knowledge to classify the syndrome accurately. Aim. To explore the feasibility of differentiation of TCM syndrome types among IgA nephropathy patients based on clinicopat...
It is estimated that 60% of anticancer drugs are derived directly or indirectly from medicinal plants. Schinus terebinthifolius Raddi (Anacardiaceae) is traditionally used in Brazilian medicine to treat inflammation, ulcers, and tumors. Because of the need to identify new antimutagenic agents and to determine their mechanism of action, this study evaluated the chemopreventive activity of the me...
Imprinted genes show parent-specific activity (functional haploidy), which makes them particularly vulnerable to epigenetic dysregulation. Here we studied the methylation profiles of oppositely imprinted genes at single DNA molecule resolution by two independent parental allele-specific deep bisulfite sequencing (DBS) techniques. Using Roche (GSJunior) next generation sequencing technology, we ...
Imprinted gene(s) on human chromosome 7q32-qter have been postulated to be involved in intrauterine growth restriction associated with Silver-Russell syndrome (SRS) as 7-10% of patients have mUPD(7). Three imprinted genes, MEST, MESTIT1, and COPG2IT1 on chromosome 7q32, are unlikely to cause SRS since epigenetic and sequence mutation analyses have not shown any changes. One hundred kilobases pr...
In infants exposed to maternal stress in utero, phenotypic plasticity through epigenetic events may mechanistically explain increased risk of preterm birth (PTB), which confers increased risk for neurodevelopmental disorders, cardiovascular disease, and cancers in adulthood. We examined associations between prenatal maternal stress and PTB, evaluating the role of DNA methylation at imprint regu...
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