نتایج جستجو برای: metaphase radial
تعداد نتایج: 67282 فیلتر نتایج به سال:
In human fertilization, the sperm centrosome nucleates a radial array of microtubules called the sperm aster. The sperm aster is responsible for apposition of male and female pronuclei, and later gives rise to the first meiotic spindle. The objective of this study was to determine microtubule assembly and chromatin configuration in rabbit oocytes following intracytoplasmic injection with human ...
Trisomy 8 is a common anomaly in bone marrow (BM) cells of patients with myeloproliferative disorders (MPD), myelodysplastic syndromes (MDS), or acute nonlymphocytic leukemia (ANLL). We studied the efficacy of fluorescence in situ hybridization (FISH) detection of trisomy 8 in patients with MPD, MDS, or ANLL using directly labeled fluorescent alpha-satellite and whole chromosome paint (WCP) DNA...
Neurons in the cerebral cortex originate predominantly from asymmetrical divisions of polarized radial glial or neuroepithelial cells. Fate control of neural progenitors through regulating cell division asymmetry determines the final cortical neuronal number and organization. Haploinsufficiency of human LIS1 results in type I lissencephaly (smooth brain) with severely reduced surface area and l...
نیاز روز افزون صنعت به استفاده از قطعاتی با هندسه ی پیچیده مانند سطوح قالب ها و پره های توربین، منجر به پیشرفت هایی در زمینه ی تکنولوژی های جدید طراحی و ساخت این نوع قطعات گردیده است. محققین از روش های مختلفی برای ساخت سریع و با راندمان بالای این سطوح استفاده کردند. از جمله ی این روش ها استفاده از استراتژی های مناسب مسیر ابزار است. استراتژی های فرزکاری علاوه بر زمان تولیدی بر روی نیروهای ماشینک...
Previous studies of the structure of metaphase chromosomes have relied heavily on electron micrography and have revealed the existence of a 10-nm unit fiber that is thought to generate the native 23-30-nm fiber by higher order folding. The structural relationship of these metaphase fibers to the interphase fiber remains obscure. Recent studies on the digestion of interphase chromatin have revea...
A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells.
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