the present investigation deals with the development of controlled release tablets of salbutamol sulphate using graft copolymers (st-g-pmma and ast-g-pmma) of starch and acetylated starch. drug excipient compatibility was spectroscopically analyzed via ft-ir, which confirmed no interaction between drug and other excipients. formulations were evaluated for physical characteristics like hardness,...

conclusions it was shown that combination of pectin and eudragits can relatively control drug release in the upper gi. on the other hand, pectin degraded in the presence of pectinase and formulations were susceptible to the colonic media. results it was shown that in the presence of pectin, formulations without erl had a relative resistance to drug release in sgf. pellets containing pectin and ...

A polystyrene-b-poly(methylmethacrylate) (PS-b-PMMA) modified with a fluorine-containing functional group at its chemical junction was designed to study the effect of on microphase separation behavior. Various molecular weights and unmodified PS-b-PMMA were synthesized, effective χ parameter for them estimated by small-angle X-ray scattering. The clearly observed in measured parameters block co...