BACKGROUND The aim of this study was to generate and evaluate new logistic regression models from simple demographic and hormonal data to predict the outcome of pregnancies of unknown location (PULs). METHODS Data were collected prospectively from 185 consecutive women classified as having a PUL by transvaginal scan; blood was taken at presentation and 48 h later to measure serum progesterone...

Reactive oxidizing species are implicated in the etiology of a range of inhalational pulmonary injuries. Consequently, various free radical scavengers have been tested as potential prophylactic agents. The sulfydryl compound, N-acetylcysteine (NAC) is the only such compound clinically available for use in realistic dosages, and it is well established as an effective antidote for the hepatic and...

BACKGROUND Persistent acute respiratory distress syndrome (ARDS) is characterized by excessive fibroproliferation, ongoing inflammation, prolonged mechanical ventilation, and a substantial risk of death. Because previous reports suggested that corticosteroids may improve survival, we performed a multicenter, randomized controlled trial of corticosteroids in patients with persistent ARDS. METH...

Two cases of lung granulomata associated with "crescentic" glomerulonephritis both in a clinical setting of polyarteritis nodosa were treated with high doses of intravenous methylprednisolone ("pulse therapy") in single injections of 30 mg/kg body-weight. In the first case rapidly progressive glomerulonephritis with 100% crescents was arrested and followed by improvement of renal function from ...

RATIONALE Immunoglobulin G4 (IgG4)-related hypophysitis is a type of IgG4-related disease (IgG4-RD), which is characterized by plasma cells infiltration in the pituitary causing functional changes and (or) space-occupying effect in the pituitary. IgG4-related hypophysitis is sensitive to hormone therapy in most patients, but recurrence is very likely. PATIENT CONCERNS Here, we report a 57-yea...

The effects of low-dose methylprednisolone as adjuvant therapy for hemophilia A patients with factor VIII inhibitorsSri Marwanta, Soetrisno Soetrisno, Bambang Purwanto, Brian Wasita, Tonang Dwi Ardyanto, Faizal Muhammad, Eti Poncorini Pamungkasari, Dono Indarto, Eillien Ramadhani Fauzi

Objective: To study the efficacy of platelet-rich plasma with Methylprednisolone in patients tennis elbow.
 Study Design: Prospective longitudinal study.
 Place and Duration Study: Department Orthopedics, Jinnah Postgraduate Medical Centre, Karachi, Feb 2019 to Sep 2020.
 Methodology: All chronic lateral epicondylitis onset symptoms greater than three months were grouped into two...