Grazing management affects ecosystem function through impacts on soil condition. We investigated the effects of long-term (over 70 years) grazing on soil properties and nitrous oxide (N2O) emission within a moderately grazed native vegetation pasture (MGP), heavily grazed native vegetation pasture (HGP), and a fertilized crested wheatgrass (Agropyron desertorum (Fisch. ex. Link) Schult.) pastur...

INTRODUCTION Vascular calcification is a common, serious and elusive complication of end-stage renal disease (ESRD). As a pro-calcifying risk factor, non-thyroidal illness may promote vascular calcification through a systemic lowering of vascular calcification inhibitors such as matrix-gla protein (MGP) and Klotho. METHODS AND MATERIAL In 97 ESRD patients eligible for living donor kidney tran...

Matrix Gla protein (MGP) is a member of the family of extracellular mineral-binding Gla proteins, expressed in several tissues with high accumulation in bone and cartilage. Although the precise molecular mechanism of action of this protein remains unknown, all available evidence indicates that MGP plays a role as an inhibitor of mineralization. We investigated the sites of gene expression and p...

The vascular endothelium is critical for induction of appropriate lineage differentiation in organogenesis. In this study, we report that dysfunctional pulmonary endothelium, resulting from the loss of matrix Gla protein (MGP), causes ectopic hepatic differentiation in the pulmonary epithelium. We demonstrate uncontrolled induction of the hepatic growth factor (HGF) caused by dysregulated cross...

In this paper, we propose a novel planner, called Moving Goal Planner (MGP) in order to adapt plans when the goal changes over time. This planner draws inspiration from Moving Target Search (MTS) algorithms. In order to limit the number of search iterations and to improve its efficiency, MGP delays as much as possible starting new searches when the goal changes. To this purpose, MGP uses two st...

The present studies demonstrate that the expression of the vitamin K-dependent matrix Gla protein (MGP) is critically dependent on cell density in culture. Subculture of confluent NRK cells to 1/30 of the confluent cell density causes a 50- to 100-fold decline in MGP expression per cell within two days. MGP expression subsequently increases with increasing cell density and eventually attains a ...

Extracellular matrix mineralization is an essential physiologic process in bone, teeth, and hypertrophic cartilage. Matrix Gla protein (MGP), an inhibitor of mineralization, is expressed by chondrocytes and vascular smooth muscle cells to inhibit calcification of those soft tissues. Tibial dyschondroplasia (TD), a skeletal abnormality apparent as a plug of non-vascularized, non-mineralized, whi...

The present study was undertaken to determine the extent of COOH-terminal proteolytic processing in matrix Gla protein (MGP), a 10-kDa protein which contains 5 residues of the vitamin K-dependent Ca2+ binding amino acid, gamma-carboxyglutamic acid (Gla). Two forms of MGP were isolated from demineralization and urea extracts of bovine cortical bone, one 79 residues in length with the COOH termin...

OBJECTIVE The antibacterial and antifungal effects of medicated gutta-percha (MGP) over different time periods have not been evaluated. The aim of this study was to evaluate and compare the antimicrobial and antifungal effectiveness of MGP and regular gutta-percha cones over different time periods using the disk diffusion method. METHODS Enterococcus faecalis, Pseudomonas aeruginosa, Staphylo...

Article history: Received 19 January 2016 Accepted 19 January 2016 Available online 21 January 2016 cardiovascular outcomes, and mortality (Liu et al., 2015). MGP acts as a strong inhibitor of soft tissue calcification. As an illustration, MGP knockout mice develop massive vascular calcification in their first weeks of life and die within 2 months of vessels' rupture (Luo et al., 1997). To acqu...