Sorafenib is an oral multi-target kinase inhibitor that has been used to treat unresectable hepatocellular carcinoma and advanced renal cell carcinoma. The aim of the study was prepare gum Arabic-chitosan (GA-CS) Arabic-modified chitosan (GA-MCS) microcapsules containing sorafenib as core phase by complex coacervation. fluorescence microscopy, dynamic light scattering (DLS), drug loading, encap...

Microcapsules are commonly used in applications ranging from therapeutics to personal care products due their ability deliver encapsulated species through porous shells. Here, we demonstrate a simple and scalable approach fabricate microcapsules with shells by interfacial complexation of cellulose nanofibrils oleylamine, investigate the rheological properties suspensions resulting microcapsules...

The encapsulated potassium ferrate(VI) (K(2)FeO(4)) samples were successfully prepared by phase separation method in organic solvents. The ethyl cellulose and paraffin were selected for the microcapsule wall materials (WM). The as prepared microcapsules were characterized by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR). The stability can be enhanced greatly when f...

The addition of liquid-filled urea-formaldehyde (UF) microcapsules to an epoxy matrix leads to significant reduction in fatigue crack growth rate and corresponding increase in fatigue life. Mode-I fatigue crack propagation is measured using a tapered doublecantilever beam (TDCB) specimen for a range of microcapsule concentrations and sizes: 0, 5, 10, and 20% by weight and 50, 180, and 460 lm di...

The dielectric relaxation characteristics and mechanism of thermochromic microcapsule-epoxy insulating materials are investigated. Results show that exhibit nonmonotonic characteristics, namely the time gradually increase with raised temperature between about 58℃—66℃, which cannot be depicted by conventional Arrhenius equation or Vogel-Fulcher-Tammann equation. It is proposed characteristic der...

High-resolution in situ autonomous visual indication of mechanical damage is achieved through a microcapsule-based polymeric material system. Upon mechanical damage, ruptured microcapsules release a liquid indicator molecule. A sharp color change from light yellow to bright red is triggered when the liberated indicator 2',7'-dichlorofluorescein reacts with the polymeric coating matrix.

Nifedipine is a hypertension drug must be consumed three times a day due to its low oral bioavailability. One way of developing a controlled drug delivery system is making nifedipine microcapsules by using environmentally friendly polymers of polylactic acid and polycaprolactone via the evaporation method using oil-in-water solvents. Polylactic acid and polycaprolactone can be said to be enviro...