On examination of a breast mass surgically excised in a 69-years-old woman, a pure invasive micropapillary carcinoma (MPC) was diagnosed (Figure 1). At close examination, intensely eosinophilic syncytial-multinucleated giant cells (CD68+) percolating the stromal bands were identified (Figure 1). The breast carcinoma illustrated here shows therefore a combination of 2 rarities, namely, an invasi...

of associated features including atrophy, inflammation and stromal reaction. Pathologic parameters of HGPIN were correlated with detection of PCa in subsequent biopsy (ies). Results: 66.7% of patients with two or more cores involved by HGPIN had PCa on subsequent biopsy. In contrast, 38.6% of patients with only one core with HGPIN were detected to have PCa (p=0.015, Fishers exact test). Tufted ...

BACKGROUND A new lung adenocarcinoma classification proposed by the International Association for the Study of Lung Cancer, American Thoracic Society, and European Respiratory Society (IASLC/ATS/ERS) has recently been published. This study aimed to investigate the utility of the new histological classification for identifying the prognostic subtypes of adenocarcinomas in stage IB patients.Corre...

BACKGROUND Pulmonary adenocarcinomas with a micropapillary component having small papillary tufts and lacking a central fibrovascular core are thought to result in poor prognosis. However, the component consists of tumor cells often floating within alveolar spaces (aerogenous micropapillary component [AMPC]) rather than invading fibrotic stroma observed in other organs like breast (stromal inva...

BACKGROUND During the past 25 years, the incidence of thyroid papillary carcinoma (TPC), especially the micropapillary subtype, has been increasing in different countries worldwide. The rise in the rate of thyroid malignancies were also determined in Turkey in the last two decades. This fact was attributed to the Chernobyl accident because Turkey is one of the affected countries by the radioact...

PURPOSE To examine the feasibility of endoscopic thyroidectomy (ET) via an axillo- breast approach without gas insufflation for large thyroid tumors and micropapillary carcinomas. MATERIALS AND METHODS The patients in the benign group were separated into groups 1 (n=95, <4 cm in tumor diameter) and 2 (n=37, ≥4 cm in tumor diameter). Also, 57 patients in the micropapillary carcinoma group unde...

This study aimed to assess the expression of p53 and Ki-67 antigen and to evaluate its relation with the other prognostic parameters in pure and partial type of invasive micropapillary carcinoma of the breast in thirty two cases. Immunohistochemical staining was performed for p53 and Ki-67 antibodies. Statistical analysis was performed for comparing the expression of p53 and proliferative activ...

OBJECTIVE According to the widely accepted pathway, a serous borderline tumor becomes invasive either by progressing into a noninvasive micropapillary tumor or directly through microinvasion. Our objective was to investigate the role of serous borderline tumors and their accompanying extraovarian lesions in pathogenesis of serous ovarian cancer using immunohistochemistry as a tool. MATERIAL A...

Purpose : We performed this study to investigate the characteristic imaging and clinicopathologic features of invasive micropapillary carcinoma of the breast. Materials and Methods: Among the 47 women with surgically confirmed invasive micropapillary carcinoma between 2005 and 2009, 32 patients (mean age, 50 years; range, 37-69 years) had all preoperative mammography, ultrasound (US) and MR ima...