Abstract Background A microsponge delivery system (MDS) is an innovative and unique way of delivering drugs in a structured manner. Using drug delivery, regulated may now be achieved quickly easily. Main body MDS comprises porous microspheres ranging size from 5 to 300 microns, with large structure very tiny spherical shape. normally used deliver via topical channels, but they have recently sho...

Purpose: The purpose of this work was to develop a prolonged microsponge drug delivery system containing dicyclomine. Methods: Dicyclomine-loaded, Eudragit-based microsponges were prepared using a quasi-emulsion solvent diffusion method. The compatibility of the drug with formulation components was established by differential scanning calorimetry (DSC) and Fourier transform infra-red (FTIR). Pr...

The purpose of this study was to design novel drug delivery system containing Lornoxicam microsponges. Lornoxicam is a Non-steroidal anti-inflammatory drug used for the treatment of various inflammatory diseases. Microsponges containing Lornoxicam and Eudragit RS 100 were prepared by quasi emulsion solvent diffusion method. The effects of drug to polymer ratios on physical characteristics of th...

Acne is a common inflammatory skin disease that mainly affects the face, neck, chest and upper back. Treatment depends on severity. Erythromycin has bacteriostatic activity which inhibits the growth of bacteria. They mainly act by binding to the 50s subunits of bacteria, 70s r-RNA complex, and protein synthesis. Erythromycin is also used topically to treat acne. They are used to treat moderate ...