Systolic ejection clicks, often associated with cardiac disease, can be distinguished from mid-systolic clicks of mitral and tricuspid origin, which are frequently benign. A different mid-systolic sound has been recognized, with timing similar to the mid-systolic clicks, which is associated with aortic insufficiency. This report describes a case in which such a sound was identified prior to aor...

mitochondrial disorders (mids) require biochemical or genetic investigations for being diagnosed. in some cases, however, the diagnosis can be suspected upon the syndromic phenotype or upon clinical presentation and family history, as in the following case. the patient was a 74-year-old male admitted for worsening of pre-existing left-sided ptosis and ophthalmoparesis after a birthday party. th...

CHEST, 78: 1, JULY, 1980 3 Barlow JB, Bosman CK, Pocock WA, et al. Late systolic murmurs and no-ejection (“mid-late”) systolic clicks: an analysis of 90 patients. Br Heart J 1968; 30:203-18. 4 Jeresaty RM. Mitral ballooning: a possible mechanism of mitral insufficiency in diseases associated with reduced end-systolic volume of the left ventricle. Chest 1971; 60: 114-5. S Winkle BA, Lopes MC, Go...

Introduction: We aimed to investigate of effect of left bundle branch block (LBBB) on perfusion and functional parameters in dipyridamole Tc99m-MIBI gated myocardial perfusion SPECT which may be helpful in interpretation of myocardial perfusion imaging. Methods: We studied 70 patients with low pre-test probability of coronary artery disease in two groups:  35 patients with LBBB and  35 subject...

A syndrome consisting of an apical systolic click and late systolic murmur appeared over a period of three months in a patient with acromegaly. Levels of growth hormone were highest during this interval. As a result of group D streptococcal endocarditis three months later, the patient sustained cerebral embolism and acquired free mitral regurgitation from ruptured chordae tendineae. During foll...

introduction: we aimed to investigate of effect of left bundle branch block (lbbb) on perfusion and functional parameters in dipyridamole tc99m-mibi gated myocardial perfusion spect which may be helpful in interpretation of myocardial perfusion imaging. methods: we studied 70 patients with low pre-test probability of coronary artery disease in two groups:  35 patients with lbbb and  35 subjects...

494 COMMUNICATIONS TO THE EDITOR CHEST, 76: 4, OCTOBER, 1979 6 Kleid JJ, Aryan SB, Martin C: Systolictime intervals in the syndrome of midsystolic click and late systolic murmur. Chest 71:85-69, 1977 7 Lewis EP, Rittgers SE, Forrester WF, et al: A critical review of the systolic time intervals. Circulation 56:146157, 1977 8 Wanderman KL, Goldberg MJ, Stack RS, et al: Left ventricular performanc...

20. Ranganathan N, Silver MD, Robinson TI, Kostuk WJ, Felderhof CH, Patt NL, Wilson JK, Wigle ED: Angiographic-morphologic correlation in patients with severe mitral regurgitation due to prolapse of the posterior mitral valve leaflet. Circulation 48: 514, 1973 21. Ranganathan N, Silver MD, Wigle ED: Mitral valve prolapse. Circulation 49: 1268, 1974 22. Grossman H, Fleming RJ, Engle MA, Levin AH...

We assessed different systolic cardiac indices to detect left and right ventricular systolic dysfunction in cirrhotic patients before liver transplantation. Between 2010-2011, 81 consecutive individuals with confirmed hepatic cirrhosis who were a candidate for liver transplantation were enrolled in this study. A total of 32 age and sex matched healthy volunteers were also selected as the contro...