HYPOTHESIS The middle ear contains homeostatic mechanisms that control the movement of ions and fluids similar to those present in the inner ear, and are altered during inflammation. BACKGROUND The normal middle ear cavity is fluid-free and air-filled to allow for effective sound transmission. Within the inner ear, the regulation of fluid and ion movement is essential for normal auditory and ...

HYPOTHESIS Studies were designed to ascertain the impact of chronic middle ear infection on the numerous ion and water channels, transporters, and tissue remodeling genes in the inner and middle ear. BACKGROUND Permanent sensorineural hearing loss is a significant problem resulting from chronic middle ear disease, although the inner ear processes involved are poorly defined. Maintaining a bal...

Previous studies of electrophysiological audiograms in gekkonomorph lizards revealed greater sensitivity in adults than in juveniles. We investigated whether this difference, as far as it is affected by the middle ear, is due to animal age or size. The velocity transfer function of the tympanic membrane (TM) was examined using laser interferometry in nine samples: adults of three large gekkonom...

The impedance of the middle-ear air space was measured on three human cadaver ears with complete mastoid air-cell systems. Below 500 Hz, the impedance is approximately compliance-like, and at higher frequencies (500-6000 Hz) the impedance magnitude has several (five to nine) extrema. Mechanisms for these extrema are identified and described through circuit models of the middle-ear air space. Th...

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BACKGROUND The diagnostic performance of endoscopic and microscopic procedures for detecting diseases of the middle ear in patients with chronic otitis media (COM) has rarely been investigated. This study was conducted to compare the performance of these procedures for identifying middle ear structures and their associated diseases in COM patients. METHODS In this prospective cohort study, 58...

Some authors have reported that significant pressure changes occured in middle ear clefts when nitrous oxide (N2O) is inhaled during general anesthesia . In 18 adult patients without ear diseases who underwent non-otological surgery , middle ear pressure measurements were made with impedance audiometer (Teledyne TA-2C) just before and during N2O anesthesia. The results obtained were as follows:...

in middle ear surgery. Concurrent improvements in the operating microscope made it possible to visualize middle ear structures in amazingly clear detail, and revealed to the ear surgeon the possibilities of preserving or restoring hearing in the surgical treatment of chronic middle ear infections. Since 1952 many articles have appeared describing various techniques of reconstructive surgery of ...

Introduction Middle ear barotrauma is the most common side effect of hyperbaric oxygen therapy. Knowledge and understanding of its pathophysiology are crucial for an accurate diagnosis and proper decision making about treatment and prevention. Objective Describe up-to-date information on pathophysiology of middle ear barotrauma after hyperbaric oxygen therapy considering the physiology of press...