BACKGROUND Poorly controlled hypertension (HTN) remains one of the most significant public health problems in the United States, in terms of morbidity, mortality, and economic burden. Despite compelling evidence supporting the beneficial effects of therapeutic lifestyle changes (TLC) for blood pressure (BP) reduction, the effectiveness of these approaches in primary care practices remains untes...

Mints/X11s are neuron-specific (Mints 1 and 2) and ubiquitous (Mint 3) adaptor proteins composed of isoform-specific N-terminal sequences and common C-terminal phosphotyrosine-binding (PTB) and PDZ domains. We now show that all three Mints bind to the cytoplasmic tail of amyloid-beta precursor protein (APP) and presenilins and strongly increase the levels of cellular APP in transfected cells. I...

PURPOSE The aim of this study was to clarify genetic and epigenetic alterations occurring during renal carcinogenesis. EXPERIMENTAL DESIGN Copy number alterations were examined by array-based comparative genomic hybridization analysis using an array harboring 4,361 bacterial artificial chromosome clones, and DNA methylation alterations on CpG islands of the p16, human MutL homologue 1, von Hi...

In this paper we introduce the transfer conception MinT that is currently being developed for the prototype of the face-to-face translation system verbmobil.1 The acronym MinT stands for Minimal Transfer. MinT is a semantic-oriented transfer model that is based on some central ideas of the MRS-based approach outlined in [Copestake et al., 1995], and the Shake-and-Bake approach to machine transl...

Four essential oils of Thyme (Thymus linearis), Lemon grass (Cymbopogon citratus), Rosemary (Rosmarinus officinalis), Mint (Mentha longifolia) and Formic Acid (65%) used at three concentrations (25, 50 and 100%) against Varroa destructor damaging honey bee Apis mellifera colonies in Honeybee Research Institute, National Agricultural Research Centre, Islamabad, Pakistan. The percentage of infest...

Aberrant amyloid β (Aβ) production plays a causal role in Alzheimer disease pathogenesis. A major cellular pathway for Aβ generation is the activity-dependent endocytosis and proteolytic cleavage of the amyloid precursor protein (APP). However, the molecules controlling activity-dependent APP trafficking in neurons are less defined. Mints are adaptor proteins that directly interact with the end...

This study was designed to determine the response of diverse mint genotypes to three commonly used cryopreservation techniques. Four mints [Mentha x piperita nothosubsp. citrata (Ehrh.) Briq.; M. canadensis L.; M. australis R. Br, and M. cunninghamii Benth] were cryopreserved using three protocols: controlled rate cooling (CC), encapsulation dehydration (ED) and PVS2 vitrification (VIT). Regrow...

of the Dissertation MiNT: A Reconfigurable Mobile Muli-hop Wireless Network Testbed

Appendectomy is the most common surgery in the world. Pain, bloat and nausea are the most side effects after appendectomy that leads to high morbidity and dissatisfaction in these patients. Herbal therapy is one the treatment .This study conducted aimed to investigate the effect of super mint on pain, nausea and bloat of patients undergoing of appendectomy. This study was a double-blind clinica...

Mints/X11s are neuronal adaptor proteins that bind to amyloidprecursor protein (APP). Previous studies suggested that Mint/X11 proteins influence APP cleavage and affect production of pathogenic amyloid(A ) peptides in Alzheimer’s disease; however, the biological significance of Mint/X11 binding to APP and their possible role in A production remain unclear. Here, we crossed conditional and cons...