تعمج تانايبلا . ةيجهنم ةعجارم تناك ةساردلا هذه :هقیرطلا و ةصالخا تاملكلا لامعتساو تانايبلا ةدعاق يف ثحبلا للاخ نم زجالحا " :یتلاا تناك ةصالخا تاملكلا .ثحبلا یف قمعتلا ريياعلما . " ةطبثلما لماوعلا " و "ءاسنلل ةدلاولا لبق ةياعرلا " لوصو" ٬" یف قمعتلا وةساردلا دعب .OR ،AND تناك ةيقطنلما لماوعلا تلااقم تددحو تضفر ةطبارتم ريغ تلااقم ، هفلتخلما تلااقلما تلااقلما رايتخلاا رايعم .تلااقلما لذل اصخلم اها...

ةــصلاـخلا : سا وه ةنيجهلا ملعتلا ةمظنأ يدحت نإ تامولعملا رداصم دحأ نم ةعبانلا تامولعملا لامعت رخآ ردصم نع ةمجانلا صئاقنلا ةنزاومل . كلذ و ةدعاو ثحب ةهجو لثمي يزمرلا يكبشلا جزملا نإ ةيزمرلا نيتقيرطلا نيب دضاعتلا نلأ ) ةيرظنلا ( ةيكبشلا و ) ةيبيرجتلا ( لآ لامعتسا نم ةيلاعف رثآأ ادح ىلع امهنم ةدحاو . لا اذه فصي ،يزمر يكبش فنصم ةطساوب ةيفرحلا ةيبرعلا غلابملا ىلع فرعتلل اماظن ثحب ،ةيلاملا غلابملا...

ناآ دقل رهوج ،ةيفخ ةفصب تامولعملا لاسرإ و لاصتلاا عوضوم مدقلا ذنم مامتهلاا و ديعب نمز ذنم عساو لكشب مدختست ةيصنلا قئاثولا تناآ ، صوصنلا يف تامولعملا ءافخلإ ةفلتخم اًقرط مويلا ىتح نمز ذنم دهشن نحن كلذل ) Text Steganography .( لاقملا اذه نإ ط لوانتي ةيبرعلا و ةيسرافلا صوصنلا يف تامولعملا ءافخلإ ةديدج ةقير . و دوآ ينويلا ةفصاوم يف دجوي ) Unicode ( ءايلا فرحل نافلتخم نازمر » ى « ، فاكلا فرحل كلذآو...

Objective(s): The aim of this study was to investigate the methylation status and mRNA expression levels of P15, death-associated protein kinase (DAPK), and suppressor of cytokine signaling-1 (SOCS1) genes in multiple myeloma (MM). Materials and Methods: The bone marrow samples of 54 MM patients were collected and the methylation status of the P15, DAPK, and SOCS1 gene promoter regions was dete...

Ubiquilin (UBQLN) proteins are adaptors thought to link ubiquitinated proteins to the proteasome. However, our lab has recently reported a previously unappreciated role for loss of UBQLN in lung cancer progression. In fact, UBQLN genes are lost in over 50% of lung cancer samples examined. However, a reason for the loss of UBQLN has not been proposed, nor has a selective pressure that could lead...

هديكچ ط ي لاس اه ي خا ي ر پ ي تفرش لباق هظحلام ا ي رد طابترا اب لولس ه ا ي نب ي دا ي لصاح هدش تسا هک ون ي د شخب هار اهراک ي ون ي ن نامرد ي رد ب ي رام ي اه ي بعص جلاعلا م ي .دشاب ا ي ن لولس اه هک رد مامت ناگرا ي مس اه ي دنچ لولس ي روضح ،دنراد اناوت يي سقت ي م و دبت ي ل هب لولس اه يي سب ي را صاصتخا ي ار هتشاد و نچمه ي ن رداق هب اج ي زگ ي ن ...

PURPOSE Suppressors of cytokine signaling (SOCS) proteins regulate the intensity and duration of cytokine signals and defective expression of SOCS1 and SOCS3 has been reported in a number of human diseases. The purpose of this study was to investigate the role of SOCS1 in intraocular inflammatory diseases (uveitis) and whether SOCS1 expression is defective in patients with ocular inflammatory d...

SOCS1(-/-) mice accumulate within the thymus and periphery CD8(+) lymphocytes that express memory cell markers and display heightened in vitro responses to common gamma-chain cytokines. To investigate whether dysregulated homeostasis of T lymphocytes and acquisition of memory phenotype by CD8(+) cells in SOCS1(-/-) mice were mediated by IL-7 and/or IL-15 in vivo, we have generated SOCS1(-/-)IL-...

Suppressor of cytokine signaling 1 (SOCS1) is rapidly induced following stimulation by several cytokines. SOCS1 negatively regulates cytokine receptor signal transduction by inhibiting Janus family tyrosine kinases. Lack of such feedback regulation underlies the premature death of SOCS1(-/-) mice due to unbridled IFN-gamma signaling. We used mouse embryo fibroblasts derived from SOCS1(-/-) mice...

صخلملا A total of 48 fresh water fishes, belonging to four species of the family Cyprinidae (Capoeta trutta, Chalcalburnus mossulensis, Cyprinion macrostomum and Leuciscus lepidus) were collected from Darbandikhan lake, southwest Sulaimaniya city, Kurdistan region, in the north of Iraq, from March to the end of July 2008. The inspection of gills revealed the infection of these fishes with four ...