Introduction: Stomach cancer is the fourth most common and second leading cause of death in world. In addition to significant costs, it imposes many problems on families that a proper justification for identifying related biomarkers. Method : The miRBASE website was used find bioinformatics information. addition, mirWALK miRNASN databases were searched miRNAs To pathways, DAVID KEGG adopted. Re...

UNLABELLED MicroRNAs (miRNAs) are a group of small, approximately 21 nt long, riboregulators inhibiting gene expression at a post-transcriptional level. Their most distinctive structural feature is the foldback hairpin of their precursor pre-miRNAs. Even though each pre-miRNA deposited in miRBase has its secondary structure already predicted, little is known about the patterns of structural con...

MicroRNAs (miRNAs) are short (~21 nt) nucleotide sequences that are either co-transcribed during the production of mRNA or are organized in intergenic regions transcribed by RNA polymerase II. In animals, Drosha, and in plants DCL1 recognize pre-miRNAs which set themselves apart by their characteristic stem loop (hairpin) structure. This structure appears important for their recognition during ...

MicroRNAs (miRNAs) are known to play critical roles in plant development and stress-response regulation, and they frequently display multi-targeting characteristics. The control of defined rice phenotypes occurs through multiple genes; however, evidence demonstrating the relationship between agronomic traits and miRNA expression profiles is lacking. In this study, we investigated eight yield-re...

•This study provides a quantitative map of 1,816 human pri-miRNA processing sites •Only 758 are confidently processed, while the majority non-canonical or false entries •We uncover atypical events such as alternative, nick, and inverse •SRSF3 is broad-acting cofactor modulating canonical pri-miRNAs Maturation microRNA (miRNA) initiated by DROSHA that cleaves primary transcript (pri-miRNA). More...

MicroRNAs (miRNAs) are a class of small non-coding RNAs, typically 22 nucleotides in length, which post-transcriptionally regulate gene expression. Mature miRNAs bind complementary sequences in the 3 untranslated region (3′ UTR) of target mRNAs and repress protein expression via a number of mechanisms including mRNA destabilisation and/or inhibition of translation [1]. So far, almost 36,000 ma...

Neuronal activity regulates a broad range of processes in the hippocampus, including the precise regulation of translation. Disruptions in proper translational control in the nervous system are associated with a variety of disorders that fall in the autistic spectrum. MicroRNA (miRNA) represent a relatively recently discovered player in the regulation of translation in the nervous system. We ha...

MicroRNAs are small (20-22 nucleotides) none coding, regulatory RNAs, whose pivotal role in gene expression has been associated in number of diseases, therefore prediction of miRNA is an essential yet challenging field. In this study miRNAs of C. roseus are predicted along with their possible target genes. A total of 19,899 ESTs were downloaded from dbEST database and processed and trimmed thro...

The pathogenesis of Bronchiolitis Obliterans Syndrome (BOS), the main clinical phenotype of chronic lung allograft dysfunction, is poorly understood. Recent studies suggest that epigenetic regulation of microRNAs might play a role in its development. In this paper we present the application of a complex computational pipeline to perform enrichment analysis of miRNAs in pathways applied to the s...