Myocarditis is a serious manifestation of systemic lupus erythematosus. It is reported that 5-10% of the patients present symptomatic myocarditis. However, myocarditis in mixed connective tissue disease is uncommon. Only a few cases with mixed connective tissue disease patients who presented symptomatic myocarditis were reported. We herein describe a patient with mixed connective tissue disease...

bipolar disorder is a mental disease that can be presented as irritable mood with affective storms, mixed symptoms of depression and mania, rapid cycles, emotional labiality and irritability during all episodes. â confirmed positive familial history of the disease is the single most robust risk factor for developing the illness. this report presents 5.5 years-old girl with the symptoms of bipol...

BACKGROUND Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described. CASE PRESENTATION We report a case of an 11-year old boy with hepatitis on admission to the hospital and symptoms and signs of ...

Sharp et al first described mixed connective tissue disease (MCTD)in 1972 as a distinct entity of connective tissue disease (1). MCTDis a disease entity characterized by overlap symptoms of systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM), as well as by the presence of antibody to U1RNRHowever, it has been suggested that rather than being reg...