AIMS To compare oesophageal motor responses to gastro-oesophageal reflux (GOR) in 16 healthy controls (group 1) and 25 reflux patients, 15 without (group 2) and 10 with (group 3) oesophagitis. METHODS All subjects underwent 24 hour ambulatory oesophageal pH measurements (5 cm above the lower oesophageal sphincter (LOS)) combined with pressure monitoring (5, 10, and 15 cm above the LOS for oes...

classic anti reflux procedures on children with a history of posterior urethral valve does not usually yield good results and often ends up with ureteral obstruction and even permanent urinary diversion. from 1981 through 1988,21 boys with history of posterior urethral valve (puv) underwent evaluation for vesicoureteral (vu) reflux 17 boys had vu reflux. following valve ablation, reflux disappe...

background: gastroesophageal reflux disease (gerd) is one of the most common gastrointestinal problems in the west while different reports indicate an increase in the prevalence in iran. the aim of this study was to estimate the preva­lence and clinical spectrum of gerd in staff of a referral hospital and evaluate the risk factors. methods: this cross-sectional study using a modified mayo clini...

results in total, 420 participants (25.7%) had gerd symptoms. risk factors with significant effects consisted of smoking, consumption of non-steroidal anti-inflammatory drugs (nasids), overeating, chronic diseases, tea and coffee consumption and gerd in spouse. conclusions the prevalence of gerd among people living in mashhad was above the average prevalence in other cities of iran. however, ri...

BACKGROUND/AIMS Transient lower esophageal sphincter relaxation (TLESR) is the main mechanism of gastroesophageal reflux disease (GERD). The aim of this study was to investigate the characteristics of transient lower esophageal sphincter movement in patients with or without gastroesophageal reflux by high-resolution manometry (HRM). METHODS From June 2010 to July 2010, we enrolled 9 patients ...

BACKGROUND AND PURPOSE Deep venous reflux resolution after great saphenous vein surgery has been reported, but the studies evaluated mainly patients with deep segmental reflux. We prospectively analyzed the effects of greater saphenous vein ablation on coexisting primary deep axial venous reflux compared with segmental venous reflux. Patients and methods Between February 1997 and June 2001, pat...

BACKGROUND/AIMS Impedance-pH monitoring allows detailed characterization of gastroesophageal reflux and esophageal activity associated with reflux. We assessed the characteristics of nocturnal reflux and esophageal activity preceding and following reflux. METHODS Impedance-pH tracings from 11 healthy subjects and 76 patients with gastroesophageal reflux disease off acid-suppressive therapy we...

BACKGROUND AND AIM The reason that some reflux episodes evoke symptoms is poorly understood, therefore the aim of this study is to assess the determinants of reflux perception in patients with non-erosive reflux disease (NERD) on proton pump inhibitor (PPI) therapy. METHODS Ten NERD patients with persistent symptoms, despite double-dose PPI therapy, were included in this study. All patients h...

Purpose: Quantitative algorithms to select patients for stripping, ligation, or banding require additional data on greater saphenous vein (GSV) diameter and valvular function.Although the final goal is to determine whether reverse flow, or reflux, is due to valvular damage, valvular absence, or vein enlargement with normal valves, this study was a first step in quantifying the influence of veno...

background gastroesophageal reflux disease is a common, chronic disease worldwide. the weekly prevalence of reflux in developed countries is 10% to 48%. it has previously been reported as 5% in asian countries, but new reports show a higher level in both asian and arab countries. in iran, reflux has increased over the last two decades. there are few studies concerning the prevalence of reflux i...