نتایج جستجو برای: modified rankin scale

تعداد نتایج: 810017  

Journal: :Stroke 2000
J M Wardlaw P A Sandercock C P Warlow R I Lindley

BACKGROUND AND PURPOSE Controversy regarding the risks and benefits of thrombolysis has not been helped by the perception that some trials were "positive" and others "negative" on their primary outcome measure of either "good" or "poor" functional outcome. We wondered whether the definition of good or poor functional outcome might have contributed to this perception, and what effect altering th...

2000
J. M. Wardlaw P. A. G. Sandercock C. P. Warlow R. I. Lindley

Background and Purpose—Controversy regarding the risks and benefits of thrombolysis has not been helped by the perception that some trials were “positive” and others “negative” on their primary outcome measure of either “good” or “poor” functional outcome. We wondered whether the definition of good or poor functional outcome might have contributed to this perception, and what effect altering th...

Journal: :Stroke 2015
Sami Curtze Susanna Melkas Gerli Sibolt Elena Haapaniemi Satu Mustanoja Jukka Putaala Tiina Sairanen Marjaana Tiainen Turgut Tatlisumak Daniel Strbian

BACKGROUND AND PURPOSE Compared with other stroke causes, small-vessel disease is associated with better 3-month outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis. Another question is the impact of coexisting cerebral white matter lesions (WMLs; a surrogate marker of small-vessel disease) on outcome, which was addressed in the current study. METHODS We anal...

Journal: :Stroke 2011
Pamela M Rist I-Min Lee Carlos S Kase J Michael Gaziano Tobias Kurth

BACKGROUND AND PURPOSE In studies enrolling patients with stroke, higher levels of prestroke physical activity are associated with better functional outcomes. However, prospective studies evaluating this association are sparse. Using a cohort of initially healthy men, we aimed to prospectively assess the association between physical activity and functional outcomes from cerebral vascular events...

2017
Michael L. James Carl D. Langefeld Padmini Sekar Charles J. Moomaw Mitchell S.V. Elkind Bradford B. Worrall Kevin N. Sheth Sharyl R. Martini Jennifer Osborne Daniel Woo

OBJECTIVE Because age affects hormonal production differently in women compared with men, we sought to define sex and age interactions across a multiracial/ethnic population after intracerebral hemorrhage (ICH) to uncover evidence that loss of gonadal hormone production would result in loss of the known neuroprotective effects of gonadal hormones. METHODS Clinical and radiographic data from p...

Journal: :Stroke 2007
Jeffrey L Saver

BACKGROUND AND PURPOSE A clinically relevant number needed to harm for tissue plasminogen activator (tPA)-related symptomatic intracerebral hemorrhage (SICH) would greatly assist therapeutic decision-making. METHODS A 15-variable prognostic model was derived from a placebo group enrolled in National Institute of Neurological Disorders and Stroke tPA Trials 1 and 2 and used to predict final gl...

Journal: :Stroke 2016
Henrik Gensicke Daniel Strbian Sanne M Zinkstok Jan F Scheitz Olivier Bill Christian Hametner Solène Moulin Andrea Zini Georg Kägi Alessandro Pezzini Visnja Padjen Yannick Béjot Sydney Corbiere Thomas P Zonneveld David J Seiffge Yvo B Roos Christopher Traenka Jukka Putaala Nils Peters Leo H Bonati Sami Curtze Hebun Erdur Gerli Sibolt Peter Koch Laura Vandelli Peter Ringleb Didier Leys Charlotte Cordonnier Patrik Michel Christian H Nolte Philippe A Lyrer Turgut Tatlisumak Paul J Nederkoorn Stefan T Engelter

BACKGROUND AND PURPOSE We compared outcome and complications in patients with stroke treated with intravenous thrombolysis (IVT) who could not live alone without help of another person before stroke (dependent patients) versus independent ones. METHODS In a multicenter IVT-register-based cohort study, we compared previously dependent (prestroke modified Rankin Scale score, 3-5) versus indepen...

Journal: :Stroke 2010
Richard B Scott Fiona Eccles Andrew J Molyneux Richard S C Kerr Peter M Rothwell Katherine Carpenter

BACKGROUND AND PURPOSE The International Subarachnoid Aneurysm Trial (ISAT) reported lower rates of death and disability with endovascular versus neurosurgical treatment of ruptured intracranial aneurysms. However, assessment of functional outcome was limited to the modified Rankin Scale, which is known to be insensitive to cognitive function. A neuropsychological substudy (N-ISAT) was therefor...

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