OBJECTIVE To evaluate and compare Mohs micrographic surgery and traditional excision in terms of cost and outcomes. DESIGN We developed a computer-simulation, probabilistic, decision model to perform a cost-effectiveness analysis, with each patient serving as his or her own control. SETTING University of Connecticut dermatology clinic, a tertiary care referral center. PARTICIPANTS Input d...

background: microcystic adnexal tumor is a rare sclerosing variant of ductal carcinoma of eccrine sweat glands which is highly invasive. this tumor is often misdiagnosed as other benign or malignant skin lesions and improper treatment is carried on and is associated with high recurrence rate. case presentation: we reported here in a 59-years old man who underwent incisional biopsy for a ongenit...

Penile squamous cell carcinoma (pSCC) is a rare disease, making it difficult to establish a standard of care, particularly in the advanced stage. We report a case of pSCC with advanced lymph node metastasis treated with multimodal therapy consisting of combination chemotherapy, irradiation, and chemosurgery using Mohs' zinc chloride-containing paste. An 80-year-old male with a past history of l...

OBJECTIVE To determine the incidence of subclinical tumor in excised facial subunits in patients undergoing reconstruction after Mohs surgery. DESIGN The study group comprised 45 patients who had their Mohs defects repaired by a facial plastic surgeon at a tertiary care center (university hospital). In the group, there were 74 biopsy-proved cutaneous neoplasms of the face. The median age of t...

OBJECTIVE To determine long-term tumor recurrence rates after treatment of primary nonmelanoma skin cancer (NMSC). Data are currently insufficient to permit evidence-based choices among treatments for NMSC. DESIGN Prospective study of an inception cohort observed for a median of 6.6 years after treatment. SETTING Dermatology clinic at a Veterans Affairs hospital. Care was provided by dermat...

AE1/AE3: anti-pan cytokeratin 1/3 ART: adjuvant radiation therapy H&E: hematoxylin and eosin IHC: immunohistochemistry SCC: squamous cell carcinoma INTRODUCTION Mohs micrographic surgery remains the gold standard for the treatment of cutaneous squamous cell carcinomas (SCCs) of the head and neck. However, for recurrent or aggressive SCCs, it can be challenging at times to ensure complete margin...

Mohs' micrographic surgery of facial basal cell carcinoma ensures a high cure rate with maximal preservation of healthy tissue. Using precise margin control, this procedure allows complete examination of all margins of tissue removed. Due to the insufficient facilities for Mohs' micrographic surgery in Sweden, only the most aggressive tumours are referred for this procedure, which could increas...

Mohs micrographic surgery allows for complete microscopic examination of the surgical margin when treating aggressive and recurrent facial basal cell carcinomas. This leads to the highest cure rates and maximal preservation of healthy tissue. The 5-year recurrence rates of 587 aggressive and/or recurrent facial basal cell carcinomas treated during 1993 to 2003 at our centre were studied retrosp...

Artificial Intelligence (AI) techniques are used for solving the intractable engineering problems. In this study, it is aimed to study the application of artificial bee colony algorithm for predicting the performance of circular diamond saw in sawing of hard rocks. For this purpose, varieties of fourteen types of hard rocks were cut in laboratory using a cutting rig at 5 mm depth of cut, 40 cm/...