نتایج جستجو برای: molecular constructs
تعداد نتایج: 678781 فیلتر نتایج به سال:
Study objectives: We tested the hypothesis that descriptors of breathlessness represent distinct and separable cognitive constructs, and predicted that the use of descriptors of breathlessness by healthy individuals is the same as their use by patients with cardiopulmonary disease. Design: Cluster analyses obtained in healthy individuals were compared with those obtained previously in patients ...
background: single domain antibodies from camel heavy chain antibodies (vhh or nanobody), are advantages due to higher solubility, stability, high homology with human antibody, lower immunogenicity and low molecular weight. these criteria make them candidates for production of engineered antibody fragments particularly in transgenic animals. objective: to study the development of transgenic chi...
Traditional cloning methods have limitations on the number of DNA fragments that can be simultaneously manipulated, which dramatically slows the pace of molecular assembly. Here we describe GMAP, a Gibson assembly-based modular assembly platform consisting of a collection of promoters and genes, which allows for one-step production of DNA constructs. GMAP facilitates rapid assembly of expressio...
The molecular computing has been successfully employed to solve more and more complex computation problems. However, as an important complex problem, the Computational Tree Logic (CTL) model checking is still far from resolved under the circumstance of molecular computing, since it is still a lack of method. To address this issue, an autonomous model checking method is presented for checking al...
Molecular and synthetic biologists have increasing demand for large, high-fidelity constructs of synthetic DNA. Recent developments in harvesting oligonucleotides from DNA microarrays has proven that these can be assembled into large constructs of DNA for costs significantly less than traditional methods. This thesis presents a complete platform for the photoelectrochemical cleavage of protecti...
nowadays, the development of anti cancer drugs is an important subject in pharmacology. bisphosphonates (b.p) are a great choice for design and production of the types of drugs which not only could perform as anti cancer agents but also could inhibit the function of acetyl cholinesterase (ache). ache hydrolyzes the acetylcholine (which is a neurotransmitter in nervous system) using the oh in i...
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