New genomic and proteomic technologies have led to important therapeutic advances in oncology. This article describes how the discovery of molecular prognostic markers to classify an individual patient’s risk of disease events and predictive markers to classify response to specific treatment options are used to guide the selection of treatment and identify targets for the development of new mol...

linked and/or gene-based molecular markers have been used widely in marker-assisted selection (mas) to differentiate resistant and susceptible genotypes. resistance to meloidogyne spp. in beta vulgaris l. is mediated by a single dominant gene (r6m-1). using allele-specific primers (asps), an snp marker harboring a single nucleotide polymorphism (a/g), linked to the resistance gene was developed...

Urtica dioica is an important medicinal plant which is widely distributed in Mazandaran province (North of Iran). In this study for the first time Amplified Fragment Length Polymorphism (AFLP) and Inter-simple Sequence Repeat (ISSR) markers were used for detection of genetic polymorphism in Mazandaran nettle. Ten AFLP primer combinations and seventeen ISSR markers were utilized. AFLP produced 830...

Molecular markers are an important tool for plant breeding. Since the 1980s, in response to technology development, molecular marker approaches have been further diversified. The establishment of new-generation sequencing and high-throughput phenotyping has greatly decreased time genotype large numbers individuals. For breeders who not very familiar with techniques want catch up advances field,...

in order to develop molecular markers based on expressed sequence tag (est) linked to fusarium head blight (fhb) resistance genes in wheat, the biological function of 8660 ests deposited in data bank were studied following which 260 ests with identified biological function were selected. in total, 62 primer combinations were designed based on conserved and non conserved sequences. linkage and q...