Objective: Impulsivity is an important neurobiological process that contributes to individual differences in substance use disorder vulnerability. Uric acid has been mentioned to be telated to some psychiatric disorders characterized by impulsivity. No other study has yet examined the relationship between UA plasma concentration and impulsivity in patients with substance use disorders. Methods:...

Two dissociable learning processes underlie instrumental behaviour. Whereas goal-directed behaviour is controlled by knowledge of the consequences, habitual behaviour is elicited directly by antecedent Pavlovian stimuli without knowledge of the consequences. Predominance of habitual control is thought to underlie psychopathological conditions associated with corticostriatal abnormalities, such ...

Obsessive-compulsive disorder is characterized by the presence of recurrent and persistent thoughts, urges or images as well as repetitive behaviors or mental acts. According to the existing evidence, it can be predicted that difficulties in emotion regulation, impulsivity and anger are related to obsessive-compulsive disorder in one way or another. The aim of the present study was to predict o...

INTRODUCTION Impulsivity, a component of the initiation of action, may have a central role in the clinical biology of affective disorders. Impulsivity appears clearly to be related to mania. Despite its relationship to suicidal behavior, relationships between impulsivity and depression have been studied less than those with mania. Impulsivity is a complex construct, and it may be related differ...

Impulsivity is a multidimensional construct, including impulsive decision-making and impulsive action, representing relatively independent neurocircuitries. ADHD is treated with methylphenidate, a drug that binds to dopamine transporters. This study in 24 adult male patients with ADHD shows that dopamine transporter occupancy by methylphenidate in the putamen correlates with improvements in cog...

Impulsivity is a core characteristic of pathological gambling (PG), even though the underlying structure and disorder specificity is unclear. This study aimed to explore different dimensions of impulsivity in a clinical sample including PG. Furthermore, we aimed to test which alterations of the impulsivity-related dimensions are disorder specific for PG. Participants were individuals diagnosed ...

OBJECTIVE The aim of the work described here was to measure the role of psychopathological features, specifically impulsivity and depression, in suicidality in patients with temporal lobe epilepsy (TLE). METHODS Neuropsychiatric evaluation of 66 outpatients with TLE was performed with the following instruments: a structured clinical interview (Mini International Neuropsychiatric Interview Plu...