INTRODUCTION Male breast cancer (MBC) is a rare disease that accounts for <1% of breast cancer cases. The most common treatment is modified radical mastectomy (MRM). Recently, breast conservative surgery (BCS) is getting popular for MBC treatment. We report a case and reviewed the literature to investigate whether emerging BCS can be considered as an alternative of a more radical surgery. PRE...

We compared the reproducibility of multiple reaction monitoring (MRM) mass spectrometry-based peptide quantitation in tryptic digests from formalin-fixed, paraffin-embedded (FFPE) and frozen clear cell renal cell carcinoma tissues. The analyses targeted a candidate set of 114 peptides previously identified in shotgun proteomic analyses, of which 104 were detectable in FFPE and frozen tissue. Al...

Various solar broadband models have been developed in the last half of the 20th century. The driving demand has been the estimation of available solar energy at different locations on earth for various applications. The motivation for such developments, though, has been the ample lack of solar radiation measurements at global scale. Therefore, the main goal of such codes is to generate artifici...

Knowledge acquisition plays a critical role in constructing a knowledge-based system (KBS). It is the most time-consuming phase and has been recognized as the bottleneck of KBS development. This paper presents a matrix representation and mapping (MRM) approach to facilitate the effectiveness of knowledge acquisition in building a KBS. The proposed MRM approach, which is based on matrix represen...

PC+GPC level (measured with P MRSI) displayed as ratios of the MR signal in tumour to normal appearing brain tissue, for each patient. References: [1] Podo, NMR Biomed, 1999;12:p413 [2] Abaogye, Cancer Res, 1999;59:p80 [3] Klomp, MRM,2008;21:p444 [4] Wijnen, ISMRM2009, #135 [5] Klomp, MRM 2006;55:p271 [6] Scheenen, MRM 2008;59:p1 [7] Cheng, Cancer Res, 1998;58: p1825 [8] Opstad, NMR in biomed, ...

Multi-resolution modeling (MRM) is widely used in manufacture industry, environment science (climate, geometry, map), science (material, biology) and so on. Dozens of theories and methods are proposed to MRM. However, most of these MRMs are not designed for simulation, which leads to MRM failures in terms of information loss, consistency maintenance and resolution changes. To solve these failur...

Previous work demonstrated the power of three-dimensional (3D) magnetic resonance microscopy (MRM) to follow complicated morphologic development in the embryonic cardiovascular system. In this study we describe a new dual-contrast method for specimen preparation that combines perfusion fixation and immersion in fixative with macro- and small molecular gadolinium agents to provide enhanced defin...

INTRODUCTION Since the first application of magnetic resonance microscopy (MRM) on large single cells (1), MRM has developed over the last 25 years as a complementary microimaging technique with a variety of applications ranging from materials to biological tissues (2). Several large single cells have been successfully imaged (3). Recently, using new surface microcoils to improve sensitivity, w...

BACKGROUND Systematic reviews favor a better body image and sexual activity in patients who have undergone conservative breast surgery (BCS) compared to modified radical mastectomy (MRM). In those patients with the same survival, MRM remains the surgical choice among both surgeons and patients in Iran as well as in many other countries. This cross-sectional study focuses on health-related quali...

Precursor ion scan and multiple reaction monitoring scan (MRM) are two typical scan modes in mass spectrometry analysis. Here, we developed a strategy by combining stable isotope labeling (IL) with liquid chromatography-mass spectrometry (LC-MS) under double precursor ion scan (DPI) and MRM for analysis of thiols in 5 types of human cancer urine. Firstly, the IL-LC-DPI-MS method was applied for...