The homodimeric glycoprotein, anti-mullerian hormone (AMH), described over 70 years ago by A. Jost, is the least studied member of transforming growth factor beta superfamily. Despite antitumor activity AMH discovered at end last century, creation effective drugs based on hindered primarily lack information mechanism various forms interaction with a specific type II receptor (MISRII). Previousl...

Anti mullerian hormone (AMH) is a homodimeric glycoprotein belonging to the transforming growth factors (TGF-β) super family. AMH plays a fundamental role in the regression of mullerian ducts in male embryo. In boys, it is significantly produced in Sertoli cells of testes until puberty and then slowly decreases to residual values for the rest of the men’s life. In female, it is secreted by gran...

ii To my family and friends who supported me throughout this journey iii ACKNOWLEDGMENTS This project would not have been possible without Drs. Donna and Mark Santillan. I would like to thank them both for their endless support and advice in the development of this program. Thanks to Dr. Kristi Borowski for allowing us access to her serum tissue bank and birth certificate data, and to Dr. Ben L...

background: this study aimed to evaluate the strength of anti?mullerian hormone (amh) and follicle stimulating hormone (fsh) in reflecting the antral follicle count (afc) in infertile females. materials and methods: this cross?sectional study was conducted on 160 females, visiting infertility clinic for assisted reproduction. serum samples collected on the 3rd day of the cycle were assayed for ...