نتایج جستجو برای: multifunctional drug delivery system

تعداد نتایج: 2865406  

2008
O. Taratula R. Savla I. Pandya H. Geng A. Wang T. Minko H. He

The rationale for this study is to develop a multifunctional nanomedicine platform for siRNA targeted delivery to cancerous tumors as well as the use of MRI as a non-invasive strategy to monitor the drug therapy outcome. Therefore, we propose a novel multifunctional gene delivery vector by combining the magnetic properties of iron oxide nanoparticles and their ability to package siRNA strands i...

Journal: :biomacromolecular journal 2015
behafarid ghalandari adeleh divsalar ali komeili mahbube eslami-moghadam ali akbar saboury

to answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. in the present paper, controlled metal based drug (pd(ii) complex) release manner of β‑lactoglobulin (β-lg) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...

Journal: :Kagaku To Seibutsu 2004

Journal: :Chemical communications 2015
Liang Huang Lijiao Ao Wei Wang Dehong Hu Zonghai Sheng Wu Su

A multifunctional drug delivery vehicle consisting of a tubular shaped silica host, a compact superparamagnetic iron oxide nanoparticle layer and a hyaluronic acid surface coating was developed as a theranostic platform, for in vivo MR imaging and magnetically guided/cancer targeted drug delivery.

Journal: :Particle & Particle Systems Characterization 2013

Journal: :Chemical communications 2012
Haihua Xiao Lesan Yan Yu Zhang Ruogu Qi Wenliang Li Rui Wang Shi Liu Yubin Huang Yuxin Li Xiabin Jing

A multifunctional hybrid platinum(IV) prodrug, which consists of both the mitochondria-targeting drug DCA and the DNA-crosslinking drug cisplatin, was synthesized and tethered to a carrier polymer to further self-assemble into micelles for intracellular delivery.

2016
Xuechuan Gao Xiao Hai Huricha Baigude Weihua Guan Zhiliang Liu

An advanced multifunctional, hollow metal-organic framework (MOF) drug delivery system with a high drug loading level and targeted delivery was designed and fabricated for the first time and applied to inhibit tumour cell growth. This hollow MOF targeting drug delivery system was prepared via a simple post-synthetic surface modification procedure, starting from hollow ZIF-8 successfully obtaine...

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