BACKGROUND Trichoepithelioma is a rare benign skin lesion that originates from hair follicles. Trichoepitheliomas are mostly seen in the scalp, nose, forehead, and upper lip. METHODS We present a large family of Iranian origin with 15 individuals affected with multiple familial trichoepithelioma in four generations, and treated with three different methods. RESULTS Trichoepithelioma is his...

Background and Aim: Basal cell carcinoma (BCC) is considered to be the most common malignancy in humans and occurs primarily in the skin especially in the head and neck region. Considering the high recurrence rate of the tumor, finding a marker for prediction of recurrence is very important. Cancer stem cells are a small subpopulation in the tumors that are related to tumorigenesis and recurren...

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Basal cell carcinoma (BCC) is the most common malignant tumor of the skin, which originates from the basal cell layer of the skin. It is more common in white race with skin types I and II. Some predisposing factors are sunlight, ionizing radiation, arsenic salts, PUVA and scar. We present a case of BCC, which appeared over an old scar of localized cutaneous leishmaniasis in a 49-year-old woman.

Background & Objectives:  CD10 is a cell surface enzyme with metalloendopeptidase activity, also known as Common Acute Lymphoblastic Leukaemia Antigen, which mainly serves as a marker for acute lymphoblastic leukemia (ALL). To date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed CD10 expression in cutaneous epithelial neoplasms. Our goal was to d...

background trichoepithelioma is a rare benign skin lesion that originates from hair follicles. trichoepitheliomas are mostly seen in the scalp, nose, forehead, and upper lip. methods we present a large family of iranian origin with 15 individuals affected with multiple familial trichoepithelioma in four generations, and treated with three different methods. results trichoepithelioma is histolog...

Basaloid follicular hamartoma (BFH) is a rare and benign adnexal tumor that resembles basal cell carcinoma (BCC) may present with different clinical manifestations. A mutation in the PTCH gene, involved Gorlin-Goltz syndrome, could be associated pathogenesis of this neoplasm. We describe case 7-year-old girl multiple papules on her face.