Motor unit number estimation (MUNE) is a method which aims to provide a quantitative indicator of progression of diseases that lead to loss of motor units, such as motor neurone disease. However the development of a reliable, repeatable and fast real-time MUNE method has proved elusive hitherto. Ridall et al. (2007) implement a reversible jump Markov chain Monte Carlo (RJMCMC) algorithm to prod...

Article history: Received 19 October 2017 Accepted 19 October 2017 Available online 19 October 2017 mune function that become highly dysregulated during carcinogenesis. However sequencing-based methods are more resource-consuming and affectable by many factors in library construction, sequencing platform. Therefore, mining the crucial factors/microbes in fecal microbiota and developing cost-eff...

415 5. Varga EA, Kerlin BA, Wurster MW. Social and ethical controversies in thrombophilia testing and update on genetic risk factors for venous thromboembolism. The effect of aspirin on haemostatic activity in the treatment of chronic venous leg ulceration. Pemphigus foliaceous (PF) is generally a benign autoim-mune blistering disease, but in some patients lesions are severe with serious implic...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which attacks the motor system. Current treatment for sporadic ALS or Cu, Zn superoxide dimutase 1 (SOD 1 mutation) familial ALS, produces only a modest increase in survival. Riluzole, has been available since 1995 and remains the only disease modifying therapy available for ALS. Using the statistical motor unit number est...

Muscle motor unit numbers decrease markedly in old age, while remaining motor units are enlarged and can have reduced neuromuscular junction transmission stability. However, it is possible that regular intense physical activity throughout life can attenuate this remodeling. The aim of this study was to compare the number, size, and neuromuscular junction transmission stability of tibialis anter...

Therapy-related acute myeloid leukemia (t-AML) is a heterogeneous group of myeloid neo‐ plasms occurring as an overwhelming complication in patients receiving previous cytotoxic chemotherapy and/or radiation therapy used to treat haematopoietic or solid malignancies or associated with immunosuppressive treatment for non-neoplastic rheumatologic/autoim‐ mune diseases or solid organ transplantati...

Influence of protein deficiency on immune response to sheep red blood cells was investigated in rats and mice with Jerne's plaque-forming cell technique. Protein deficiency resulted in a reduction in the number of antibodyproducing cells consequent upon a prolongation of cell generation time in rats. Injection of syngeneic thymocytes brings about better improvement in the im mune response of th...