We perform a large-scale meta-analysis of 51 peer-reviewed 3xTg-AD mouse publications to compare Alzheimer's disease (AD) quantitative clinical outcome measures, including amyloid-β (Aβ), total tau, and phosphorylated tau (pTau), with cognitive performance in Morris water maze (MWM) and Novel Object Recognition (NOR). "High" levels of Aβ (Aβ40, Aβ42) showed significant but weak trends with cog...

To examine the isolated effects of altered currents in cerebellar Purkinje neurons, the authors used Scn8a-super(flox/flox), Purkinje cell protein-CRE (Pcp-CRE) mice in which Exon 1 of Scn8a is deleted only in Purkinje neurons. Twenty male Purkinje Scn8a knockout (PKJ Scn8a KO) mice and 20 male littermates were tested on the Morris water maze (MWM). Subsequently, half were tested in 500-ms dela...

The use of commercially available cation and anion exchange membranes to generate power from industrial wastewater obtained from three different industries (food, alcohol and dairy factories) without the addition of external microorganisms or chemicals by using microbial fuel cells (MFCs) was investigated. The results indicate that the original mixed culture of microorganisms presented in waste...

[Purpose] The purpose of this study was to investigate the effects of ankle joint mobilization with movement on knee strength, ankle range of motion, and gait velocity, compared with weight-bearing exercise in stroke patients. [Subjects and Methods] Thirty subjects with chronic stroke were divided into three groups: MWM (n = 12), WBE (n = 8), and control (n = 10). All groups attended physical t...

Wireless local area networks have demonstrated significant promise for the support of high bitrate multimedia communication. However, the performance of wireless LANs is degraded due to frequent network impairments which result in bit-errors and packet losses. To cater for such impairments, real-time applications and protocols tailored for wireless networks are introducing enhanced error robust...

bstract—We found that a single week of exercise enhanced ognitive function on the Morris water maze (MWM), such hat exercise animals were significantly better than sedentary ontrols at learning and recalling the location of the platform. n order to elucidate the role that calcium calmodulin protein inase II (CAMKII) holds in mediating the exercise-induced nhancement in learning and memory, a sp...

Many studies have indicated the importance of capturing scaling properties when modeling traffic loads; however, the influence of long-range dependence (LRD) and marginal statistics still remains on unsure footing. In this paper, we study these two issues by introducing a multiscale traffic model and a novel multiscale approach to queuing analysis. The multifractal wavelet model (MWM) is a mult...

[Purpose] This study compared the EMG activities of the plantarflexor and dorsiflexor muscles during inclined walking with and without modified mobilization with movement (modified MWM) using tape in women with limited ankle dorsiflexion. [Subjects] Fifteen women with limited dorsiflexion in their feet (22 feet in total) were recruited for this study. [Methods] The subjects walked with and with...

OBJECTIVE The purpose of this study was to compare the efficacy of Mobilization with Movement (MWM) and kinesiotaping (KT) techniques with a supervised exercise program in participants with patients with shoulder pain. METHODS Twenty subjects with shoulder pain were included if subjects were diagnosed by the referring physician with either rotator cuff lesion with impingement syndrome or impi...