1. Programa de Pós-Graduação em Clínica Médica, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro (RJ) Brasil. 2. Departamento de Ciências Biológicas, Escola Nacional de Saúde Pública Sérgio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro (RJ) Brasil. 3. Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Ri...

Title: Natural history of Mycobacterium fortuitum pulmonary infection presenting with migratory infiltrates: A case report with microbiological analysis Authors: Satoshi Okamori ([email protected]) Takanori Asakura ([email protected]) Tomoyasu Nishimura ([email protected]) Eiko Tamizu ([email protected]) Makoto Ishii ([email protected]) Mitsunori Yoshida ([email protected]) ...

Mycobacterium peregrinum is a nonpigmented rapid growing nontuberculosis species belonging to the Mycobacterium fortuitum group. The draft genome of M. peregrinum type I CSUR P2098 comprises 7,109,836 bp exhibiting a 66.23% G+C content, 6,894 protein-coding genes, and 100 predicted RNA genes. Its genome analysis suggests this species differs from Mycobacterium senegalense.

Mycobacterium boenickei is a rapidly growing mycobacterium isolated for the first time from a leg wound in the United States. Its 6,506,908-bp draft genome exhibits a 66.77% G+C content, 6,279 protein-coding genes, and 59 predicted RNA genes. In silico DNA-DNA hybridization confirms its assignment to the Mycobacterium fortuitum complex.

Disk diffusion is one method of susceptibility testing of the Mycobacterium fortuitum complex to antibacterial agents. We utilized disks of polymyxin B (300 U), amikacin, and kanamycin to determine whether they could also be used for species identification when compared with standard biochemical methods. With the polymyxin disk, 100% of 75 M. fortuitum strains produced zones of inhibition, wher...

OBJECTIVES Some clinical isolates of Mycobacterium fortuitum are naturally resistant to macrolides, e.g. clarithromycin. Thus, the aim of this study was to identify the gene(s) conferring this resistance. METHODS M. fortuitum ATCC 6841T DNA libraries were screened for plasmids that complemented the macrolide-susceptible phenotype of Mycobacterium smegmatis variant ermKO4 [erm(38)-negative]. M...

N ontuberculous mycobacteria rarely cause keratitis. Most reported cases have been described in compromised corneas (ie, after penetrating keratoplasty, refractive surgery, and contact lens wear). The most frequently recovered nontuberculous mycobacteria are the rapid growers, Mycobacterium fortuitum and Mycobacterium chelonae. Occasional cases of keratitis caused by the slower-growing Mycobact...

Myco. fortuitum was isolated from subcutaneous abscesses of two patients who had been inoculated with B.C.G. and one patient who had iron injections. The organisms were resistant to a wide range of anti-tuberculous drugs. They were highly virulent for mice in which they produced symptoms of spinning disease. It is thought that the infections originated from contamination of syringes or skin.