In Korea, Mycoplasma pneumoniae was detected in 255/2,089 respiratory specimens collected during 2000-2011; 80 isolates carried 23S rRNA gene mutations, and 69/123 culture-positive samples with the mutation were resistant to 5 macrolides. During 2000-2011, prevalence of the mutation increased substantially. These findings have critical implications for the treatment of children with mycoplasma ...

This manuscript reviewed the literature on infection by Mycoplasma pneumoniae with emphasis on etiological aspects of childhood community-acquired pneumonias. Bibliographical research was carried out from Pubmed Medline, MDConsult, HighWire, LILACS, and direct research over the past 10 years with the following keywords: Mycoplasma pneumoniae, pneumonia, and childhood. Fifty-four articles were s...

In a previous communication (2), the fine structure and location of a mycoplasma-like agent in experimentally infected mouse lung was described. The agent which caused a chronic pneumonia in mice was originally derived from laboratory rats with naturally acquired chronic pneumonia, as defined by J. R. M. Innes et al. (3), and it was found to be indistinguishable from the grey lung agent (1). Al...

Background A number of studies have outlined mechanisms by which mycoplasma infection may promote allergic lung inflammation. In addition, there is increasing evidence from human studies suggesting that mycoplasma infection contribute to asthma exacerbations, and severity with the change of cytokines. The present study evaluated the change of serum levels of eosinophil count, eosinophil cationi...

A fatal case of interstitial pneumonia caused by Mycoplasma pneumoniae with fulminant evolution into diffuse interstitial fibrosis is reported. Treatment with tetracycline and corticosteroids failed to arrest the progress of the disease. Fatal Mycoplasma pneumoniae infections have been reported previously and some degree of pulmonary fibrosis has been described in a few cases but as far as coul...

PCR assays of naso- and oropharyngeal samples among hospitalized children appear equally effective for the diagnosis of serologically confirmed community-acquired mycoplasmal pneumonia. However, the combination of results from both sites yields optimal sensitivity (57%), specificity (98%), and positive (92%) and negative (82%) predictive values when compared with Mycoplasma pneumoniae enzyme-li...

Introduction Mycoplasma hyopneumoniae causes enzootic pneumonia that primarily affects growing pigs. Although the disease is nonfatal, it causes substantial losses attributable to reduced growth performance, increased susceptibility to secondary bacterial pneumonia, and potentiation of PRRSV-induced pneumonia.1, 2 Both cell-mediated and humoral immune responses appear to be important in providi...

We read with great interest the article by LIEBERMAN et al. [1] published in this journal last December regarding community-acquired pneumonia in the Beer-Sheva area of Israel. We were especially interested in their results regarding Mycoplasma infections. They found the peak incidence of pneumonia caused by Mycoplasma to be during spring, but not in the winter months (p=0.054). Furthermore, th...

BACKGROUND This study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients. MATERIALS AND METHODS The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed. RESULTS Compared with the CAP group, cellular dysplasia in respiratory tract epithe...