BACKGROUND The recommendations in guidelines are based on evidence; however, there is a gap between recommendations and clinical practice. OBJECTIVE To describe the practice of prescribing evidence-based treatments for patients with acute coronary syndrome in Brazil. METHODS This study carried out a subanalysis of the ACCEPT registry, assessing epidemiological data and the prescription rate...

We investigated the preventive effects of long-term treatment with the angiotensin converting enzyme inhibitor ramipril on myocardial left ventricular hypertrophy and capillary length density in spontaneously hypertensive rats. Rats were treated in utero and subsequently up to 20 weeks of age with a high dose (1 mg/kg per day) or with a low dose (0.01 mg/kg per day) of ramipril. Animals given a...

Acute myocardial infarction is one of the main causes unusual death. However, diagnosing acute based on post-mortem examination may be difficult; notably, it cannot diagnosed inspection. In this study, we aimed to investigate usefulness cardiac marker analysis in diagnosis and review possibility its application inspections. This study included 69 autopsy cases, including 29 cases which interval...

Introduction: Coronary Artery disease is one of the major causes Mortatlity I world that included Myocardial ischemia and infarction. Cardiac toponins are (troponin- Troponin -T) markers myocardial they sign damage. They can provide important diagnostic prognostic information. Aim : In present study correlation clinical presentation, complication outcome with reference different level (mild, mo...

Experimental myocardial infarction was produced in 32 mongrel dogs. The changes in activity of four lysosomal enzymes (acid phosphatase, glucuronidase, deoxyribonuclease, and •y-glutamyl-transpeptidase) were examined in the soluble and the particle-bound fraction. The pattern of changes in free and particle-bound enzyme activity observed was similar for all four enzymes. During the first 48 hou...

1. The crucial role played by the renin-angiotensin-aldosterone system in the cardiovascular system and the immense therapeutic potential of angiotensin-converting enzyme inhibitors and, more recently, angiotensin II receptor blocking agents, in both heart failure and post-myocardial infarction is becoming increasingly evident. Polymorphisms within the genes controlling this enzyme system are c...

Non-Q wave myocardial infarctions, also known as nontransmural myocardial infarctions or subendocardial myocardial infarctions, have been managed as "mild" coronary events in the past. Substantial evidence now requires modification of this approach. Because of their tendency to be associated with modest cardiac enzyme level elevations, non-Q wave infarcts often result in a favorable early or in...