introduction: leptin, secreted from adipose tissue may have some correlation with coronary artery disease according to some reports in literature. the mean concentration of plasma leptin in patients with normal and abnormal myocardial perfusion imaging (mpi) and relation of leptin levels, independently to abnormality in mpi after correction for body mass index (bmi) was evaluated. methods: as a...

OBJECTIVES Obstructive sleep apnoea (OSA) might cause right ventricular dysfunction and pulmonary hypertension. We aimed to determine the effects of nasal continuous positive airway pressure (CPAP) therapy on right ventricular myocardial performance index (MPI) in OSA patients without hypertension. METHODS 49 subjects without hypertension, diabetes mellitus, any cardiac and pulmonary disease ...

The rat infarct model is widely used in heart failure research, but few echocardiographic indexes of left ventricular (LV) function are validated in this model. Accordingly, the objective of this study was to validate a 13-segment LV wall motion score index (WMSI) and the myocardial performance index (MPI) in infarcted rats. Twenty-nine male Wistar rats underwent left coronary artery ligation o...

Introduction: Leptin, secreted from adipose tissue may have some correlation with coronary artery disease according to some reports in literature. The mean concentration of plasma leptin in patients with normal and abnormal myocardial perfusion imaging (MPI) and relation of leptin levels, independently to abnormality in MPI after correction for body mass index (BMI) was evaluated. Methods...

background: pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. the aim of this study was to evaluate whether spect/ct myocardial perfusion imaging (mpi) could be used for assessing sheep myocardium following an acute myocardial infarction (mi) and response to int...

The rodent model of myocardial infarction (MI) is extensively used in heart failure studies. However, long-term follow-up of echocardiographic left ventricular (LV) function parameters such as the myocardial performance index (MPI) and its ratio with the fractional shortening (LVFS/MPI) has not been validated in conjunction with invasive indexes, such as those derived from the conductance cathe...

Background Regadenoson (Lexiscan; Astellas) is a new vasodilator myocardial stress agent that selectively activates the A2A receptor. Unlike adenosine, regadenoson is easier to administer and results in fewer side effects. Although extensively studied in patients undergoing nuclear myocardial perfusion imaging (MPI), its performance in cardiovascular magnetic resonance (CMR) MPI remains unknown...

Background—Color Tissue Doppler Imaging (TDI) M-mode through the mitral leaflet is an easy and precise method to estimate all cardiac time intervals from one cardiac cycle and thereby obtaining the Myocardial Performance Index (MPI). However, the prognostic value of the cardiac time intervals and the MPI assessed by color TDI M-mode through the mitral leaflet in patients with ST-segment Elevati...

OBJECTIVE Sleep apnea-hypopnea syndrome (SAHS) is an emerging disease with considerable cardiovascular impact. The myocardial performance index (MPI) is an echocardiographic parameter that is useful in the assessment of global myocardial function. The purpose of this study was to identify any differences in the MPI between patients with and without SAHS. PATIENTS AND METHODS We studied 120 co...

Background: Pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. The aim of this study was to evaluate whether SPECT/CT myocardial perfusion imaging (MPI) could be used for assessing sheep myocardium following an acute myocardial infarction (MI) and response to int...