Introduction: The relationship between depression and coronary artery disease is well established; however assessment of this relationship using functional and semi-quantitative imaging (myocardial perfusion scintigraphy) was lacking. The aim of this study was to assess the relationship between the severity of depression and the severity of myocardial perfusion abno...

Fixed myocardial defects in both stress and rest images, could be artifactual as a result of soft tissue attenuation. To increase specificity and identify the false positive results, we used gated technique to evaluate the wall motion and wall thickening as an index to differentiate real ischemic lesions from artifactual defects. 93 patients were studied. In 46 patients (48.8%) fixed perf...

Dear Sir, the recent issue of Nuclear Medicine Review published an interesting study by Gholamrezanezhad et al. regarding rate dependent left bundle branch block and its effect on myocardial perfusion SPECT [1]. They reported four cases with rate dependent LBBB during exercise stress for myocardial perfusion imaging. Myocardial perfusion SPECT imaging showed no evidence of reversible perfusion ...

UNLABELLED The aim of this study was to determine the effect of perfusion defect and imaging sequence on the evaluation of myocardial stunning with gated perfusion SPECT. METHODS A dynamic mathematic cardiac torso phantom was used to create 100 gated SPECT simulations (50 stress-rest and 50 rest-stress sequences) with a wide range of perfusion defects. No segmental wall motion abnormalities w...

Background—Harmonic power Doppler imaging (HPDI) is a novel technique for assessing myocardial perfusion by contrast echocardiography in humans. The purpose of this study was to compare myocardial perfusion by HPDI with that obtained by Tc-sestamibi single photon emission computed tomography (SPECT) during rest and pharmacological stress. Methods and Results—HPDI was performed on 123 patients w...

BACKGROUND Harmonic power Doppler imaging (HPDI) is a novel technique for assessing myocardial perfusion by contrast echocardiography in humans. The purpose of this study was to compare myocardial perfusion by HPDI with that obtained by (99m)Tc-sestamibi single photon emission computed tomography (SPECT) during rest and pharmacological stress. METHODS AND RESULTS HPDI was performed on 123 pat...

BACKGROUND The purpose of this study is to compare sensitivity, specificity and accuracy of myocardial perfusion SPECT for the detection of coronary artery disease (CAD) in women and men. MATERIAL AND METHODS 588 patients (455 males and 133 females, 273 after a previous myocardial infarction) underwent stress myocardial perfusion SPECT. The accuracy of myocardial perfusion SPECT was proved by...

BACKGROUND Myocardial perfusion gated single photon emission computed tomography (SPECT) can be used for non-invasive detection of coronary artery stenosis and cardiac allograft vasculopathy (CAV), which is a crucial factor for the long-term survival of heart transplant (HTx) recipients. A frequently observed finding in myocardial perfusion imaging of patients after HTx is inhomogeneous myocard...

Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically. Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be ...