myocyte enhancer factor 2

How broadly expressed transcription factors contribute to tissue-specific gene expression is not well understood. Andzelm, Cherry et al. (2015) demonstrate that myocyte enhancer factor 2D (MEF2D) binds and activates retina-specific regulatory regions by cooperative interaction with the tissue-specific transcription factor CRX.

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The Positive Transcription Elongation Factor b Is an Essential Cofactor for the Activation of Transcription by Myocyte Enhancer Factor 2

Journal: :Journal of Molecular Biology 2008

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ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003

Lidong Liu Jane E Cavanaugh Yupeng Wang Hiroyuki Sakagami Zixu Mao Zhengui Xia

Extracellular signal-regulated kinase 5 (ERK5) is a member of the mitogen-activated protein kinase family whose biological function in the CNS has not been defined. In contrast to ERK1 and ERK2, which are activated by neurotrophins (NTs), cAMP, and neuronal activity in cortical neurons, ERK5 is activated only by NTs. Here, we report that ERK5 expression is high in the brain during early embryon...

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Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors.

Journal: :Proceedings of the National Academy of Sciences 1993

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Interactions between mitochondria and the transcription factor myocyte enhancer factor 2 (MEF2) regulate neuronal structural and functional plasticity and metaplasticity

Journal: :The Journal of Physiology 2015

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