Myxedema coma is a rare and potentially life-threatening condition that occurs when severe hypothyroidism untreated or inadequately managed. It characterized by rapid drop in mental status, hypothermia, respiratory failure, hypotension, other symptoms of metabolic dysfunction. The primarily affects older women with history thyroid dysfunction but can occur any age gender group. A common trigger...

Over a 5-year period, three cases of thyrotoxic pretibial myxoedema were encountered. The incidence of pretibial myxoedema in Chinese thyrotoxic patients in Singapore was 0-7yo (03y. in females and 1F6% in males). One of the three patients also had thyroid acropachy. The incidence of thyrotoxic pretibial myxoedema in Singapore is compared with that in the literature and the aetiology briefly re...