Though lipomas are very common tumors occurring in the head and neck region, there are very few case reports of submucosal lipomas of the upper aerodigestive tract. A case of myxoid lipoma of the supraglottic region is reported.

OBJECTIVES To analyze the expression and distribution pattern of extracellular matrix components in pleomorphic adenomas of the major and minor salivary glands and to compare the morphological findings of these tumors with the immunohistochemical expression, considering the different types of stroma predominating in each case. METHODS AND RESULTS The expression of tenascin (TN) and fibronecti...

Introduction. Myxoid lesions may present as benign, locally invasive, or malignant tumors. The incidence of intramuscular myxoma is nearly 1 case in 1,000,000 inhabitants. Case report. A 73-year-old man presented to our clinic with a painless, subcutaneous tumor the adductor region left thigh. Computed tomography and magnetic resonance imaging showed cystic thin septae located muscles. was exti...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Solitary fibrous tumors (SFTs) most commonly occur in the pleura, but may also occur in the...

myoepitheliomas are benign tumors which account for less than 1% of all salivary gland tumors. in this article, we report the clinical, pathologic, and immunohistochemical features of plasmacytoid myoepithelioma of the hard palate in a 73-year-old man having a painless hard palate mass with progressive growth for one month who was admitted in alzahra hospital of isfahan university of medical sc...

A subset of sarcomas is associated with specific chromosomal translocations that give rise to fusion genes believed to participate in transformation and oncogenesis. Identification of the primary cell environment that provides permissiveness for the oncogenic potential of these fusion genes is essential to understand sarcoma pathogenesis. We have recently shown that expression of the EWS-FLI-1 ...

Introduction. Aggressive angiomyxoma is a rare, slowly growing, and benign tumour of mesenchymal origin, which affects women of reproductive age and is associated with a high risk of local recurrence. Case Presentation. A case of a 47-year-old white female is presented herein, with a large polypoid, gelatinous mass on the right labia majora, measuring 26 × 21 × 6 cm. Histopathologically, the le...

Activating mutations of platelet-derived growth factor receptor α (PDGFRA) are detected in a significant proportion of gastrointestinal stromal tumors (GISTs), in addition to the more frequent mutation in c-kit. GISTs with PDGFRA mutations have been found to have several characteristic morphological features, sometimes allowing to discriminate them from GISTs with c-kit mutations. Among these, ...

Dear Editor, Neurothekeomas are rare benign dermal tumors, which originate from the peripheral nerve sheath. They are divided into myxoid, intermediate, and cellular types, based on the amount of myxoid matrix and on the immunohistochemical study. We report an unusual S-100 negative case of myxoid neurothekeoma, which is currently described in the literature as a new type of neurothekeoma. A 73...

Gastrointestinal stromal tumors (GISTs) have a rather wide morphologic spectrum. Here, we report a rare variant plexiform GIST in gastric antrum. Microscopically, the tumor showed plexiform or multinodular growth pattern, proliferation of spindle cells, presence of epithelioid cells, and abundant myxoid stroma with thin-walled blood vessels. The histologic features were similar to plexiform fib...